CJ viene convinta dal fratello che l'esperienza del liceo è orribile e che perderà i suoi migliori amici, Fenwick e Crispo. Questo pensiero la terrorizza!

CJ organizza un'ultima avventura con i suoi migliori amici, Fenwick e Crispo, terrorizzata dall'idea che il liceo possa separarli.

CJ è sicura che dentro ognuno di noi si nasconda un superpotere ed è determinata a trovare il suo e quello dei suoi amici.

CJ, Fenwick e Crispo decidono di seguire la regola del sì che consiste ne dire sì a qualsiasi cosa per un'intera giornata di scuola.

Tra le 100 cose, c'è anche "mettere su una band", perciò quando i professori propongono un festival di musica, si presenta per CJ, Fenwick, e Crispo l'occasione di spuntare questa voce dalla lista.

A sleepover fund-raiser is held at school, and CJ and her pals want to stay awake for the event, but it's no easy task.

CJ longs for a pet, but her mom is unsure she's ready, so she makes CJ look after a flour baby to prove she's responsible.

CJ and her pals experiment with their wardrobes and learn about the effects clothes can have.

CJ works with Fen and Crispo to find out their "special thing".

Crispo lacks funds for a concert ticket, so his pals scheme to get him one without him knowing they paid for it.

CJ and the boys decide to expand their group, but making new friends throws each of them into unexpected situations.

The group decides to enter the science fair, but CJ cannot figure out what she wants to do and starts losing her spirit; however, Ronbie raises her spirits back up with a pep talk. Meanwhile, Fenwick builds a robot that is beaten by Mindy's better robot. Crispo tries multiple things to impress one of the judges, but repeatedly fails. Eventually, CJ figures out that she can enter her list of 100 things to do before high school because of the science of whether or not things on the list prepare someone for high school and Fenwick builds a robot that highly surpasses Mindy's, but it goes haywire and wrecks everyone's science fair projects, except Crispo's, whose science fair project ended up being himself because of what his body can do.

When Crispo joins the Save the Baboons club, which is ran by Mindy and Blake, CJ and Fenwick, who were not allowed to join, try to find their own clubs. Fenwick joins the Super Genius club and CJ joins the Club club, which is boring. CJ and the other club members attempt to make it cooler, but it gets taken over by Mindy and Blake's club, so CJ tries one more time in a bigger room. When Crispo discovers that the money donations for the Save the Baboons club is going toward the club's expenses rather than saving the baboons, he leaves and join CJ's Club Awesome club, which becomes a huge success. However, it becomes too much of a success after Mindy's not able to go in, despite everyone being able to join, and CJ, Fenwick, and Crispo not even being allowed to go back in due to the club reaching capacity.

Due to a bad childhood experience, Principal Hader cancels the Halloween carnival. CJ, Fenwick, and Crispo make it their thing to figure out why Principal Hader hates Halloween and fix it. Meanwhile, Crispo is made fun of for wearing what others perceive as a costume for little children. He then changes to a more dark costume to be cool, but later realizes that he should not change simply because somebody doesn't like a particular feature about him.

CJ challenges her friends to sit at another lunch table during lunchtime and see how events occur differently.

CJ and her friends discover the challenges of taking care of themselves when they find that they are home alone for the night

CJ and the boys decide to make their voices heard during the 7th grade elections; a friendly competition turns negative

When a simple lie morphs into an out of control event, CJ and the boys discover the power of words and the messy business surrounding lies, truths and the consequences of telling both.

The children are ready to redeem their rewards for a school achievement trip to the water park, but their "pootybucks" go missing.

CJ, Fen and Crispo try to find their own unique ways of creating lasting memories of their time at Pootatuck.

The friends plan to meet their idols, but when their carefully laid plans begin to unravel they realize the importance of patience.

The gang becomes inspired by the fact that it takes 10,000 hours to master something, so they decide to master their own things.

Crispo attempts to overcome his fear of asking for help in class; CJ volunteers to escort fifth grade students through the school; Fenwick tries to become the high five king of middle school.

After Ronbie's girlfriend dumps him, CJ and the boys decide to take the initiative and get their hearts broken.