Habituals de la temporada 6

1. 

   Melissa Benoist

   Kara Danvers / Supergirl / Kara Zor-El

2. 

   Chyler Leigh

   Alex Danvers / Sentinel

3. 

   David Harewood

   J'onn J'onzz / Martian Manhunter

4. 

   Jeremy Jordan

   Winn Schott

5. 

   Calista Flockhart

   Cat Grant

6. 

   Mehcad Brooks

   James 'Jimmy' Olsen / Guardian

Estrelles convidades 9

1. 

   Dean Cain

   Jeremiah Danvers

2. 

   Jenna Dewan

   Lucy Lane

3. 

   Brit Morgan

   Leslie Willis / Livewire

4. 

   Michael Mealor

   Fratty Dude

5. 

   Tom Waite

   Pilot

6. Jay Jackson

   Male Newscaster

7. 

   Malina Weissman

   Young Kara Zor-El

8. Jordana Taylor

   Young Alex Danvers

9. 

   Helen Slater

   Eliza Danvers

Equip tècnic 4