Säsongens återkommande skådespelare 9

1. 

   Nick Gehlfuss

   Dr. Will Halstead

2. 

   Yaya DaCosta

   April Sexton

3. 

   Torrey DeVitto

   Dr. Natalie Manning

4. 

   Rachel DiPillo

   Sarah Reese

5. 

   Colin Donnell

   Dr. Connor Rhodes

6. 

   Brian Tee

   Dr. Ethan Choi

7. 

   Marlyne Barrett

   Maggie Lockwood

8. 

   S. Epatha Merkerson

   Sharon Goodwin

9. 

   Oliver Platt

   Dr. Daniel Charles

Gästskådespelare 18

1. 

   DeRon J. Powell

   Tate Jenkins

2. 

   Karen Aldridge

   Dr. Kendra Perrington

3. 

   Mace Montgomery Miskel

   Eric Jenkins

4. 

   Christina Brucato

   Claire Rhodes

5. Justin McCarthy

   Mr. Newman

6. 

   Vanessa Martinez

   Neela Desai

7. Robert Eli

   Brian Tucker

8. Taylor Marie Blim

   Ellie Newman

9. Walter Briggs

   Andrew Tucker

10. 

    Jeanne T. Arrigo

    Ms. Allen

11. 

    Aurora Adachi-Winter

    Margaret

12. Adrian Jumaane Hill

    Basketball Player

13. 

    Michael-Andre Smith

    Tate's Friend

14. Deverin Deonte

    Tate's Friend #2

15. 

    D.W. Moffett

    Cornelius Rhodes

16. 

    Roland Buck III

    Noah Sexton

17. 

    Amy J. Carle

    Dr. Olga Patchefsky

18. 

    Lorena Diaz

    Nurse Doris

Medarbetare 2