An auto accident sends Goodwin into a spiral as she tries to help a young boy and his mother. Natalie's secretive behavior begins to draw the attention of Dr. Marcel and Dr. Halstead.

Scott and Archer diagnose a pregnant woman with a serious infection. Maggie receives shocking news. Halstead and Charles question an elderly patient’s Alzheimer’s diagnosis. In an effort to help a patient, Marcel takes a risk.

Halstead and Asher clash over a patient in need of a kidney transplant. Marcel faces a tough decision when Blake is in surgery. Choi and Archer treat the son of Med's general counsel. Med's family grows.

Charles and Cuevas clash over the treatment of a paranoid patient. Choi treats a pregnant patient from Asher's past. Marcel and Taylor help a man who needs a risky neurosurgery.