Dr. Choi treats a teen mother who abandoned her newborn baby in an alley, as the staffers must make difficult decisions about the teen's future. Also, a hypochondriac with chest pains is treated, as is a patient suffering from possible dementia.

Dr. Manning returns from maternity leave and treats a teen with a history of medical issues. Meanwhile, Dr. Choi cares for a former Navy shipmate; a Saudi prince arrives for a surgical procedure, but only from a hotshot surgeon; and a romance blooms between Sarah and a lab tech.

Nurse Lockwood gets arrested when she takes a stand. Meanwhile, Dr. Halstead deals with a pending lawsuit against him; a baby's injuries come into question; Dr. Charles faces personal issues; and suspicions rise about a patient who was hit by a car.

Dr. Rhodes convinces Dr. Latham to join him for a medical trip out of town. Dr. Manning treats an 8 year-old cancer patient who wants to give up on his battle. Elsewhere, an unhealthy woman with heart problems is brought in and doesn't want to listen to doctors. Meanwhile, Dr. Choi, Dr. Charles and Dr. Reese work on a complicated case involving a woman with a personality disorder.

Dr. Choi helps a patient with chronic pain find a solution. Dr. Halstead considers a new path. Dr. Charles and Anna bond over a scary situation.

As Maggie deals with her own trauma, she steps in to help a mother in need. Dean continues to stir the pot with more than one doctor. A patient comes to Med needing immediate treatment, but doesn't want it from them.

Stevie’s personal and professional worlds collide when her mother becomes her patient. Dylan’s history with the father of a patient interferes with his perception of a case. Crockett's allegiances are challenged when his patient's liver is a potential match for one of Dr. Blake's patients.

Supply chain disruptions dramatically impact Med, causing Marcel to clash with other doctors. Maggie reveals something to Ben. Choi and Archer help a patient with ALS.

Goodwin and Charles clash as negotiations drag on between the administration and the custodial workers' union. Asher fights to keep a mother and her newborn baby together.

The hospital is in disarray when the janitors go on strike. Marcel treats a young girl injured on her family's farm. Charles and Cuevas' schizophrenic patient returns to Med.