Dr. Halstead jeopardizes his career when he goes against a family's order regarding a terminally ill cancer patient. Meanwhile, April and Dr. Reese treat a homeless man, and Choi's personal issues emerge while caring for a bipolar patient.
Nurse Lockwood gets arrested when she takes a stand. Meanwhile, Dr. Halstead deals with a pending lawsuit against him; a baby's injuries come into question; Dr. Charles faces personal issues; and suspicions rise about a patient who was hit by a car.
A husband makes a request following his wife's death; Dr. Charles tries to reason with a patient who wants to remove his own arm from his body; a child arrives at the hospital after swallowing magnets; Sarah has last-minute thoughts about her residency.