After Jane discovers Mateo’s abduction, chaos ensues, especially when they all learn Sin Rostro is involved and demanding a ransom. Jane must also focus on motherhood and turns to Xo and Alba for help, leaving Rafael feeling left out. Meanwhile, Petra is conflicted with what to do with Rafael’s remaining sperm sample.

When a slot opens up in the graduate program that Jane has been waiting for, she is faced with her first big motherhood dilemma -- leaving Mateo sooner than expected. Rafael is still reeling from Petra's news as he tries to help plan Mateo's baptism with Jane. Xo helps Rogelio confront his past even though it makes Xo uncomfortable. Meanwhile, Michael takes some advice from Rogelio about how to handle Jane, but it is easier said than done for him.

As Jane tries to juggle motherhood and school, she forgets to plan Lina's surprise 25th birthday party leading to friction between the best friends. Rafael tells Jane that he still wants a romantic relationship with her, but she is blindsided when he asks for joint custody. Petra tries to enlist Michael's help to keep Jane and Rafael apart. Rogelio's ex-wife, Luciana, is blackmailing him with secrets from years ago to get her role back on "The Passions of Santos." Meanwhile, Michael gets a new partner and a possible lead in the Sin Rostro case.

Jane thinks she is finally ready to make a decision about her love life. Alba has taken the proper steps to become a citizen, but Xo's past might make it more difficult than anyone was expecting. Rogelio learns that his nemesis, Britney Spears, is at the Marbella Hotel and he is determined to confront her about their past. Michael is so caught up in his ongoing feud with Rafael that he ends up in big trouble at work. Meanwhile, Petra gets an offer from her ex Milos she just can't refuse.

Jane and Rafael begin estate planning for Mateo, but when Jane realizes that Mateo will inherit millions, she worries he will become spoiled. Jane is also finally starting graduate school, but her professor is not sympathetic to her situation. Rogelio's famous show is ending, so he decides to create his own show, with Xo's encouragement. Petra is shocked to learn what she is having and turns to Jane for advice and help in getting her mother out of prison. Meanwhile, after Michael's issues at work, he has decided to go rogue and is even more determined to catch Sin Rostro.

Jane and Rafael interview potential babysitters to help take some of the pressure off everyone, but Jane has specific and lengthy requirements. Jane attends her graduate school's Christmas party in hopes of finding the perfect writing advisor, but things don't go quite as planned. Rogelio is faced with a tough decision about the direction of his life. Petra wants a friendship with Jane, but her mother's antics once again thwart those efforts. Meanwhile, Michael's suspicions have turned out to be true and he thinks he has discovered a lead on a possible rival to Sin Rostro.

Jane and Rafael are still at odds with each other as they are about to celebrate Mateo's first Christmas. Jane discovers that the scholarship she thought she had been awarded isn't quite that and now needs to find a way to pay for grad school. Rogelio has employed an intern and is having trouble trusting him. Petra is struggling with the latest dilemma her mother has gotten them into. Meanwhile, Michael is trying to find Luisa's mother who he now suspects is not dead and may be involved with Sin Rostro.

Jane's latest parenting obstacle is sleep training Mateo, a struggle that has the Villanueva woman divided on what is the best method. At the same time, she is beginning her new job as a TA and is faced with a class full of basketball players looking for an easy A. Petra confesses all to Rafael and is determined to put her mother away for good. Rogelio's mother Liliana comes for a visit and reveals a 40 year old family secret. Meanwhile, Michael discovers the truth about Luisa's mother and new information about Rafael's mother.

In the middle of the night, Jane gets a burst of creative energy and starts her thesis. Unfortunately, Mateo spills orange juice all over her computer causing it to crash and Jane loses all her hard work. When Jane brings her computer to be fixed, she meets Dax and with the urging of her friend Lina (guest star Diane Guerrero), Jane considers dating again. Rogelio decides to have his mother Liliana become his manager, but soon realizes that was not the best decision. When Rafael comes to after being attacked by his mother now known to be the crime lord Mutter, he goes to Michael.

Jane's crush on Professor Chavez is popping up in her dreams and she needs to evaluate her feelings towards him. Xo and Jane find Liliana's engagement ring and think that Rogelio is going to propose. Rogelio IS planning to propose, but with a different ring, one that gets swallowed accidentally by Mateo! Michael.

Jane is considering whether or not to take her relationship with Jonathan to the next level and turns to Xo for advice. Xo and Rogelio have their own relationship issues to work out. Meanwhile, as a favor to Rafael, Jane agrees to help Petra by throwing her a baby shower. Luisa is in a terrible car accident, but all is not as it seems. Michael comes to a realization he must share with Jane.

Jane and Michael are back together – almost! Jane attempts to get Rafael and Michael to reconcile, but it doesn’t go well. While Rafael is sulking over losing Jane, he is ignoring Petra and her pregnancy needs. Xo and Rogelio have broken up over the baby issue, but they are still acting like a couple, something Jane sees as a problem. Rogelio hires a new assistant, Paolo, who appears too good to be true.

Jane and Michael are back together and Jane wishes she had never left Michael in the first place. Rafael appears to have regressed to his playboy ways and Petra is concerned about him. But Petra is not aware that Rafael is helping Michael find Mutter's other son, Derek. Rogelio's new assistant, Paolo, is actually his stalker Lola. Finally, Petra gives birth to the twins.

Rafael and Petra are new parents but Petra is already back to work and appears to be not interested in motherhood. Xo has invited Alba's old flame Pablo to visit. This does not sit well with Alba as she believes Pablo is cursed and will bring bad luck. Jane is growing concerned that she can't get in touch with her father, Rogelio, who is being held captive by Lola.

Jane and Michael's wedding plans are side tracked when the Villanueva house is ruined by a flood. Jane is looking to have a small wedding, but Rogelio wants nothing more than to throw Jane a big blow out wedding so he can invite all his celebrity friends. Jane and Michael are also looking for the perfect home to move into and when they find a place 45 minutes away, Rafael has an issue being that far from Mateo. Petra is still having trouble adjusting to motherhood.

Jane has a specific idea of how she wants to celebrate her bachelorette party, but when Xo and Lina get involved, nothing goes as planned. Michael wants to enjoy a night out with his friends, but things get awkward when his future father-in-law, Rogelio, tries to plan the perfect bachelor party. Rafael is still trying to figure out what his half-brother Derek motives are and what he knows about their mother. Meanwhile, Petra gets a surprise of a lifetime.

With Jane and Xo still dealing with the fallout from Jane's bachelorette party, Jane is now left with finding someone to watch Mateo. When Michael volunteers to help everything is perfect until Mateo does something for the first time in front of Rafael, upsetting him. Rogelio gets in trouble with the network executives when he uses the crew for his own use, so he turns to his favorite writer Dina to help fix the problem. Meanwhile, someone is causing problems for Petra at the Marbella and in her personal life. 

Jane takes on additional shifts at the Marbella to make some extra money, but it starts cutting into her time with Mateo. Jane and Rafael agree that they need a formal custody agreement and decide to use a mediator to help make it more amicable. Xo takes an acting role on Rogelio's telenovela and they are both surprised with her performance. Michael gets called into his boss' office after a newspaper runs a story on him and Sin Rostro. Meanwhile, Petra confronts Rafael when she learns that the twins' trust fund is different from Jane's arrangement.

The Villanueva women have a tradition for Mother's Day and Jane is excited to get to participate in her first one as a mom. However, their plans are thwarted when Petra invites everyone to a brunch instead. Jane's TA position is put into jeopardy when a mysterious ad appears in the college newspaper. Rogelio is hurt when Dina doesn't invite him to her birthday party, so he asks Jane to help in an unusual way. Rafael finds himself in big trouble thanks to his half-brother. Meanwhile, Xo finds herself in a compromising position.

Jane has made big plans to celebrate Mateo’s first birthday, but things start to fall apart when she learns there might be an issue with her wedding venue. Rogelio faces a challenge on set that could jeopardize Jane’s big day. Jane is excited when Alba gives her a lead on a book publisher, but soon begins having doubts about her writing. Jane and Petra try to help Rafael figure out his troubles, but they have differing opinions on how to handle the situation. Meanwhile, Michael is convinced that Derek is really in cahoots with Mutter and has a plan to prove it.

After moving up the wedding day, Jane and Michael find all their carefully made plans thrown into chaos. To make matters worse, Jane is unhappy with her current graduate thesis, but changing it might put a wrinkle in her big day. Rafael still has feelings for Jane, but is torn about whether he should speak now or forever hold his peace. Petra has her own family drama when Anezka has a medical emergency and ends up in the hospital. Meanwhile, Rogelio and Xo are finally coming to terms with the state of their relationship until Xo gets surprising news.