En militärkonvoj bombas på en bro i New Orleans och Pride jobbar under täckmantel för att hitta en stulen missil. Han måste förhindra en attack mot ett amerikanskt fartyg och klockan tickar.

The NCIS team investigates the murder of a blogger dedicated to exposing government corruption and cover-ups and discovers a Navy Seal and CIA humanitarian mission with a dark secret.

When a female combat pilot and Navy hero dies in an air-show plane crash, the NCIS team must investigate if it’s the fault of the pilot or the new jet that was just approved to deploy to bases globally.

Special Agent Pride is sent a partner from the Australian Defence Force Investigation Service, Special Agent Naomi Parsons, after an Royal Australian Navy Lieutenant, who was key to international negotiations on nuclear weapons, is murdered in New Orleans.

The team’s participation in the annual Red Dress Run is cut short when a Petty Officer is found dead in the French Quarter from a drug overdose.

The life of a genius Navy coder employed by Brody’s mother, Olivia Brody, hangs in the balance after the heart intended for his transplant is stolen. Olivia joins the NCIS team as they race to locate the missing organ.

Pride and Sonja are ambushed after traveling to Texas to escort a key witness for the trial of an infamous arms dealer who Pride apprehended.

The fiancé of Pride's daughter's friend goes missing during a blackout; and the team locates the man's dead body, which holds clues to the cause of the blackout.

The murder of a Marine provides new clues in the first case Pride and Lasalle ever worked together, just before Hurricane Katrina struck the city and washed away any evidence. Also, the team celebrates Thanksgiving together in Pride’s bar.

A string of Christmas burglaries turns deadly and the evidence leads the NCIS team to Wade’s adopted son, Danny. Also, Lasalle and Brody tease Sonja about the high stakes of drawing Pride in the team’s Secret Santa holiday exchange.

While Special Agent Pride and the New Orleans team investigate a Russian sleeper agent who was involved with Abby’s brother, Luca, Sebastian flies to D.C. to partner with Abby on the forensics in the case. Also, Bishop drives through the night to deliver a package and work the case with the New Orleans team.

The crossover starts on NCIS S13E12 Sister City (I).

The team investigates the murder of an immigrant petty officer that was staged as a suicide. Also, the agents secretly create an online dating profile for Pride.

A Mardi Gras party at Pride's bar ends up being cut short after he and Mayor Douglas Hamilton are abducted by some unknown assailants.

When a mystery man saves the life of a Lieutenant and then disappears from the scene, the NCIS team unravels a new case when forensic evidence suggests he is a soldier who was captured in Afghanistan years ago and never found.

After tracking stolen Navy TNT to a cocaine warehouse, Special Agent Pride and the NCIS team uncovers a domestic drug ring that is producing their own cocaine and headed by Sonja’s childhood friend, Marion Watkins.

A Navy captain ends up being murdered during an appearance on a local radio show. Pride's daughter returns home to discuss her plans for the future.

Agent Brody realizes that there is a connection between the case of a sailor hit by a party bus and the death of her sister.

The NCIS team discovers a surveillance van filled with photos documenting Special Agent Pride’s every move after his daughter Laurel is attacked on campus and placed in protective custody.

The NCIS team investigates the murder of a Navy Lieutenant during a French Quarter second line funeral procession, a New Orleans tradition that celebrates the recently deceased with a musical street parade.

After a Navy lieutenant dies during a clandestine visit to a general’s hotel room, Special Agent Pride and the NCIS team are asked to break standard protocol for the murder investigation.

A Navy culinary specialist is the target of an explosion while visiting her family’s 100-year-old restaurant in the French Quarter. Also, Brody is in D.C. tracking a lead in the General leak case.

The NCIS team partners with Homeland Security after the murder of a Navy master diver is linked to chatter of a foreign attack on the city.

The NCIS team uncovers a mole in the ranks while working with the Department of Homeland Security to locate 900 missing pounds of explosives that pose an imminent threat to New Orleans.