The new Secretary Of State Elizabeth McCord finds herself immediately faced with a maelstrom of difficult political challenges with an international hostage situation being her most important challenge.

Elizabeth has to deal with a crisis in Yemen and there's trouble on the home front for her as well after her oldest daughter Stevie manages to make the headlines for protesting a new policy at her university.

Elizabeth is confronted by a hostile reporter who is threatening to publish confidential documents. Elsewhere, Henry is stuck in an international negotiation when his wife uses his job as leverage to make a deal with Pakistan.

Elizabeth negotiate's with Iran over their nuclear program. Jason works with his Dad on a school report.

Elizabeth faces unexpected consequences when she makes a plea to the President to help with a dire situation in Western Africa.

After Elizabeth takes Alison with her to India on her first state department trip abroad, she is soon in crisis mode after a huge earthquake hits that causes an explosion at an American-owned factory. She is also separated from Alison.

Henry ends up being reactivated by the president into the NSA and he decides to keep his continued involvement in the spy game a secret from Elizabeth.

Elizabeth, Henry and Isabelle investigate a plane crash that killed former Secretary of State Vincent Marsh. Nadine reenters the dating scene after she agrees to go on a date with a NASA scientist.

A deranged gunman manages to leave the State Department in lockdown. Matt has some information to tell Daisy's fiance.

Elizabeth, Henry and Isabelle work together to find former Secretary of State Vincent Marsh’s secret bank account, but soon uncover that one of Elizabeth’s staff members already has access to it.

When a Texas state trooper is killed by a Mexican cartel smuggler, Elizabeth arranges an extradition deal before going on vacation to celebrate her 25th wedding anniversary in New York City. However, when political issues arise around the case, she is forced to cut their trip short.

Elizabeth pushes for the prosecution of a Bahraini diplomat after he is caught holding a maid hostage in his home. Also, Henry's father comes to visit.

Elizabeth is humiliated at a public budget hearing when her staff fails to find the corruption that exists in her microloan program. Also, the investigation into Marsh's death continues.

Elizabeth heads to Turkey to mend political relations after the Turkish government releases a video that could be damaging to the CIA. Also, Jason is threatened with expulsion after punching a bully at school.

Elizabeth secretly travels to Iran in an attempt to prevent a coup that could impact President Dalton’s administration. Also, she brings her staff up to speed on the investigation into Marsh’s death.

As Elizabeth struggles to hold herself together emotionally following the attack in Iran, she works to prevent an ecological disaster in the Amazon, and prepares for a national television appearance on “Face the Nation.” Also, she and Henry disagree about the level of protection Jason should have at his new school.

While Elizabeth seeks a diplomatic solution to a doomsday cult in Bolivia, a congressman attempting to negotiate with its leader is taken hostage. Meanwhile, Elizabeth and Henry meet Stevie’s much older boyfriend.

Elizabeth and President Dalton work together to solve the Greek debt crisis, but not everyone at home is happy with the agreement. Meanwhile, Henry mulls over a new job offer, and Stevie reconnects with her childhood friend, the President’s son.

While Henry is in Russia giving a lecture on fundamentalism, Elizabeth must navigate tricky political waters when a Russian nuclear submarine vanishes in American waters. Also, Stevie breaks up with her older boyfriend.

As Elizabeth prepares for the arrival of Iranian President Shiraz to sign a nuclear treaty, she uncovers a top secret plot to assassinate him on United States soil. At the same time, she must deal with a massive protest by the Human Rights Campaign in response to Iran’s plans to stone a gay citizen to death. Also, Elizabeth sees a therapist (Marsha Mason) to deal with her PTSD.

When Elizabeth confronts her former friend Juliet, she flashes back to when then-CIA Director Dalton offered her a job that would have changed the course of her life. Also, Stevie and President Dalton’s son, Harrison (Jason Ralph), begin a relationship that will have consequences.