Ryuko Matoi is a vagrant school girl traveling from place to place searching for clues to the truth behind her father's death - the "woman with the scissor blade". The journey leads Ryuko to Honnouji Academy.

The final confrontation is at hand! Will Ragyo and Nui bring on the end of the world, or will Ryuko and the others be able to stop them?

It's graduation at Honnouji Academy, but not everything is as it seems. Ryuko Matoi and the gang must defeat their final enemy.