CBI consultant Patrick Jane, Senior Agent Teresa Lisbon and her team investigate the double murder in Palm Springs of a pro golfer's wife and her doctor, which has the hallmarks of a serial killer with a personal connection to Jane.

While Lisbon and her team investigate the murder of a young waitress in the Napa Valley, Jane goes behind Lisbon's back to orchestrate his own undercover operation using Van Pelt as bait.

Enticed by the promise from a convicted murder that he'll reveal information about Red John upon his release, Patrick Jane becomes singularly focused and quits the CBI in order to prove the prisoner is innocent.

A story of greed and betrayal pits Patrick Jane against a group of financiers when the CBI investigates a series of murders at a corporate retreat in the wilds of the Sierra Nevada foothills.

Lisbon fears that the serial killer Red John is drawing Patrick Jane into a trap when the CBI team investigates the murder of a young girl and the abduction of her twin sister.

Jane and Lisbon learn that the Red John case has been reassigned to a different CBI team led by the straight-shooting officer Sam Bosco.

Even after Bosco arrests Jane and puts him in prison for spying on him, Jane is able to help the CBI team from his cell to solve the murder of a young man.

When Dr. Alicia Seberg, a government research scientist, is exposed to a deadly toxin while at work and has only hours to live, she calls Patrick Jane and the CBI to find her murderer.

Patrick Jane and Kristina's first date is interrupted by a report of Red John striking again, which is discovered to be a copycat. But when Kristina reaches out to the real Red John, both she and Jane find themselves in grave danger.

When the CBI investigates the kidnapping of a prominent lawyer and state house lobbyist, the CBI Director wants Jane on the case, but he is uncertain of his future with the unit after his encounter with Red John.

Patrick Jane accepts the help of a local astrologer, Ellis Mars, to solve the puzzling case of a triple homicide that involves two policemen and the fiancé of an EMT worker.

Patrick trades Hightower's secret location to Laroche for the four remaining names on his list. The team then sets up a trap to uncover Red John's real informant, leading to a possible face-to-face showdown between Patrick and Red John.

In prison for killing his nemesis, Patrick Jane must prove that the man he shot really was Red John. Meanwhile, Lisbon urges Van Pelt to seek counseling in the aftermath of the death of her fiancé.

Jane suspects that Agent Susan Darcy has ulterior motives when she asks for his help with a homicide investigation. Meanwhile, the CBI team handles the murder of a young woman who was killed after meeting someone in an online chat room.

After another failed attempt to defeat Red John, Patrick Jane hits rock bottom, finds a lover and shoots one of his own.

While Jane tries to decipher Lorelei’s connection to Red John, the CBI team is forced to partner with the FBI to solve the murder of a hotel employee.

Just as Jane narrows down the Red John suspect list to seven, Red John strikes again, and the victim has a link to Jane’s past.

Jane and Lisbon secretly continue their mission to narrow down the list of seven Red John suspects as they investigate the murder of a man who was missing for two years.

Patrick Jane finally comes face-to-face with Red John, the serial killer he’s tracked since the madman murdered his wife and daughter. For 10 years, Jane has doggedly hunted his nemesis in his search for justice.

A new lead in a cold case requires Lisbon to delay her plans to leave for Washington, D.C., giving Jane time to finally come to terms with his feelings for her and decide on a course of action.

Lisbon accepts Jane's surprise marriage proposal, but a killer's quest for revenge may cost them the happy ending they've worked so hard to achieve.