A group of students stage a mock bank hold-up to publicise a charity. When the students' leader is shot dead by a bank guard, Homicide detectives have to establish whether the guard was acting within his duty or recklessly; a complication is that jealousy in the group caused the student to be 'set up' for the shooting.

For three days, a cottage in the Dandenong Ranges provides a perfect honeymoon hideaway. But then the young bride is brutally slain, and Homicide detectives find themselves investigating bigamy as well as murder.

An unidentified young woman is murdered in a park, the second such occurrence, and Homicide detectives have to race against time to prevent a third killing.

Nancy Tate is kidnapped by two men, taken to a lonely spot and murdered. A search begins for a mysterious eye-witness wearing a cap and a suede jacket.

A clerk is shot when two masked men hold up a factory and steal a $10,000 payroll. Homicide detectives have no real leads, and must rely on information from an informer, Sgt. Bronson's 'Aunt Sally'.

A body is discovered in a railway box-car at the Jolimont railway yards, from where a young boy has also gone missing. Police dogs are called in to track down the killer, a young man who has killed his father with an iron bar during an argument, and fled with the only witness - the missing boy.

Edward Heywood is reported missing, and three weeks later his body is recovered from the Yarra River. Two anonymous letters - death threats - provide the Homicide detectives with an important clue. The man's wife, Katarina, had many lovers, and when she reports her sister-in-law Norma has suicided, one of her lovers, Rogowski, makes a false confession.

When an attractive young girl is murdered, it doesn't take long for the Homicide detectives to identify her killer; but they have a tense time gathering sufficient evidence to bring him to trial, aware that before they can complete their case he may well kill again.