In Memphis, Sergeant Caroline Mason and her team respond to a convenience store shooting, where surveillance cameras captured the last few moments of a man's life. Investigators must sift through the footage for clues that will point them to the killer. And in Miami, Detectives Fernando Bosch and Ricky Martinez are called to a wealthy high-rise condo, where the crime scene blood-covered bathroom. To track down the killer, investigators follow a blood trail that leads them out of the building and into a hair-raising manhunt.

Detectives find a man murdered outside his own apartment. While hunting for the killer, they uncover the victim's inner life, revealing a man torn between who he is and what he believes; a tragic triple shooting leaves two young men dead and a third fighting for his life in the hospital. Detectives soon find out that the deadly shooter and his partner may be kids, too.

Detectives Ricky Martinez and Fernando Bosch investigate the double homicide of a husband and wife. As they race against the clock to find the killer, they discover that their best witness in the case tragically also has the most at stake; Sergeant Ron Collins and his team must solve the mystery behind a car discovered on the edge of town.

In Memphis, TN, Lt. Toney Armstrong and his team respond to a shooting where the killer may be barricaded in his apartment. Then the stand-off gives way to a dispute among friends where detectives must determine if the shooter was acting in self-defense, or not. And in Dallas, TX, Detectives Kim Sanders and Paul Ellzey start with nothing but a decomposed body, and are quickly drawn into a fast-paced manhunt to track down a mentally unstable suspect who they're afraid might hurt someone else.

Miami detectives respond to the stabbing murder of an elderly man found dead in his home. After collecting key evidence on the crime scene and talking to witnesses, Detective Rolando Garcia starts to suspect the victim's emotionally unstable nephew may have committed the murder. In Memphis, Sergeant Caroline Mason investigates the murder of a young man outside of a liquor store. She uses all her interrogation skills and street smarts to find her suspect.

Dallas Homicide Detectives respond to a call about a body in the charred remains of a car. Digging into the victim's life uncovers a dangerous lifestyle with questionable friends. With each interview, a new piece of the puzzle is revealed and investigators take one step closer to the killer. In Memphis, Sergeant Tony Mullins and his team find themselves crossing state lines into neighboring Mississippi in their hunt for the person responsible for a home invasion that left one man dead.

In Memphis, Sergeant Mitch Oliver and his team respond to the murder of a man shot in his car while parked at a local mini market. In order to track down their shooter, detectives must rely on witnesses who sometimes hide more than they reveal. And in Phoenix, Detective Rosenthal is investigating the case of young man shot dead and left in the parking lot of a local bar. His biggest lead is the bar's surveillance tape. It could reveal who the victim was with the night he was killed.

In Miami, Detectives Emiliano Tamayo and Ervens Ford find a young woman shot dead in a convenience store. The store's surveillance footage reveals she may have been an innocent victim. Another man was the target. They need to find him before it's too late. Across town, fellow Miami Detectives Fernando Bosch and Rick Martinez are investigating the murder of a man shot dead on the street in the middle of the day. The victim's girlfriend was there and may know the identity of the killer.

At a gruesome crime scene in Dallas, TX, Detective Rick Duggan finds a badly decomposed body. To solve the case, detectives delve into the victim's past leading them on a trail lined with love and deceit. In Memphis, a dead body mysteriously dumped in an empty field has Detective Tim Helldorfer and his team scrambling for leads.

On a rain-soaked Memphis morning, Sgts. Tony Mullins and Mitch Oliver respond to a drive-by shooting, and learn that the victim is an innocent bystander. The man who says he was the intended target lead Mullins and Oliver on a manhunt for two brothers alleged to be the driver and the shooter. And in Dallas, when a man is shot to death in a van, Det. Dale Lundberg must untangle a web of conflicting stories about the man's identity to try to find his killer.

In Memphis, TN, Sergeants Bill Ashton and Caroline Mason hunt for the killer of a beloved neighborhood "Candy Lady", shot through her closed front door. From the projects of the city to the trailer parks of the countryside, they leave no stone unturned in their search for the elusive killer. And in Miami, FL, Detectives Ervens Ford and Kevin Ruggiero track the killer of a 17-year old shot in the notorious Liberty City section called the "Pork and Beans". Eyewitnesses paint very different stories about the shooting and Ford and Ruggiero must sift through the lies and get to the truth before time runs out.

In Dallas, a young woman is found stabbed, beaten, and burned on a bed. The victim's 12-year-old niece and her mother are missing. Lead Detective Dale Lundberg soon discovers that this murder is extremely personal. In Memphis, Sgt. Mitch Oliver is investigating the homicide of a pool hustler found dead in a seedy motel room. The victim's car is nowhere to be found. Oliver hopes if he finds the car, he'll find his suspect.

A Memphis motel turns into a war zone when a gunfight leaves two men dead and another critically injured. Sgt. WD Merritt and the homicide team spring into action to find their shooter. In Kansas City, homicide Det. Everett Babcock leads the investigation into the shooting death of a two-year-old baby. To Babcock's surprise, an eight-year-old witness leads police on a nationwide manhunt.

Miami homicide detective Freddy Ponce is called to the brutal beating death of a homeless man. After finding what he believes is the suspect, Ponce's case takes an unexpected turn. In Kansas, a grandmother is found stabbed to death in her kitchen. Detective Ray Lenoir hunts down several potential leads, but it is the forensic evidence that finally reveals their suspect.

In Memphis/Tennessee wählt ein Tankstellenbesitzer den Notruf, nachdem auf seine Tankstelle ein Überfall verübt wurde, bei dem neben dem Besitzer noch ein weiterer Angestellter schwer verletzt wurde. Während der Besitzer im Krankenhaus behandelt werden kann, kommt für seinen Angestellten, Asefa Afsr, jede Hilfe zu spät. (Text: RTL Nitro)

Der 54-jährige Ronald Gentile aus Illinois ist zum Geburtstag seines Sohnes Paul nach Miami gereist, als er völlig unerwartet vor seinem Mietwagen niedergeschossen wird. Da die Spurensicherung bei dem Opfer weder eine Geldbörse noch Schmuck finden kann, deutet alles auf einen Raubüberfall hin. Nachdem im Mietwagen Fingerabdrücke sichergestellt werden konnten, gibt es einen Verdächtigen. Es handelt sich um einen unter anderem wegen Raubes vorbestraften jungen Mann namens Brandon Rolle. Als die Fahndung nach Brandon erfolglos bleibt, wenden sich Paul und seine Mutter mit einem Appell an die Öffentlichkeit, in dem sie Brandon dazu auffordern, sich zu stellen. (Text: RTL Nitro)

Mitten in der Nacht hören Anwohner in einem Viertel im Osten von Detroit/Michigan Lärm aus der Wohnung der 25-jährigen Siraquana Cotton. Als sie nach der jungen Frau sehen wollen, bietet sich ihnen ein Bild des Schreckens: Sowohl die junge Frau als auch deren 2-jährige Tochter wurden erschossen. Eine Nachbarin sagt aus, dass sie einen Tag zuvor noch einen Streit zwischen Siraquana und deren Ex-Freund Charles Epperson mitbekommen hätte. Da Epperson daraufhin als tatverdächtig gilt, wird er zur Fahndung ausgeschrieben. (Text: RTL Nitro)

Ein Mann namens Louis wählt in Memphis/Tennessee den Notruf, nachdem er mitansehen musste, wie ein kräftiger Mann mit einem grauen Wagen eine Frau überfahren und sie 250 Meter weit mitgeschleift hat. Für das Opfer, die 47-jährige Renee Goodwin, kommt jede Hilfe zu spät. Die Spuren führen zu einem gewissen ‚Big Bundy‘, einem der Polizei bekannten Zuhälter und Schläger. Kann Louis den Verdächtigen identifizieren? In Kansas City/Missouri wird der 21-jährige Drogendealer Jesse L. David mitten in der Nacht in der Nähe seiner Wohnung erstochen. Das Opfer hält eine Tüte Crack in der Hand und nur wenige Meter von ihm entfernt kann sein Handy sichergesellt werden. (Text: RTL Nitro)

Im Stadtteil Little Havana in Miami/Florida erstickt der 72-jährige Kubaner Victor Evora, der eine kleine Dachdeckerfirma leitet, qualvoll, nachdem er in seiner eigenen Einfahrt überfallen und mit Klebeband gefesselt wurde, während sich seine Ehefrau im Haus aufhält und nichts von dem Angriff mitbekommt. Als im Büro des Opfers Blutspuren am Safe gefunden werden, deutet alles auf einen Raubüberfall hin – bis die Ermittler von Victors Sohn erfahren, dass sein Vater vor Kurzem einen Einbrecher auf frischer Tat ertappt und ihn mit Klebeband gefesselt hatte. (Text: RTL Nitro)