In Memphis, Sergeant Caroline Mason and her team respond to a convenience store shooting, where surveillance cameras captured the last few moments of a man's life. Investigators must sift through the footage for clues that will point them to the killer. And in Miami, Detectives Fernando Bosch and Ricky Martinez are called to a wealthy high-rise condo, where the crime scene blood-covered bathroom. To track down the killer, investigators follow a blood trail that leads them out of the building and into a hair-raising manhunt.

Detectives find a man murdered outside his own apartment. While hunting for the killer, they uncover the victim's inner life, revealing a man torn between who he is and what he believes; a tragic triple shooting leaves two young men dead and a third fighting for his life in the hospital. Detectives soon find out that the deadly shooter and his partner may be kids, too.

Detectives Ricky Martinez and Fernando Bosch investigate the double homicide of a husband and wife. As they race against the clock to find the killer, they discover that their best witness in the case tragically also has the most at stake; Sergeant Ron Collins and his team must solve the mystery behind a car discovered on the edge of town.

In Memphis, TN, Lt. Toney Armstrong and his team respond to a shooting where the killer may be barricaded in his apartment. Then the stand-off gives way to a dispute among friends where detectives must determine if the shooter was acting in self-defense, or not. And in Dallas, TX, Detectives Kim Sanders and Paul Ellzey start with nothing but a decomposed body, and are quickly drawn into a fast-paced manhunt to track down a mentally unstable suspect who they're afraid might hurt someone else.

Miami detectives respond to the stabbing murder of an elderly man found dead in his home. After collecting key evidence on the crime scene and talking to witnesses, Detective Rolando Garcia starts to suspect the victim's emotionally unstable nephew may have committed the murder. In Memphis, Sergeant Caroline Mason investigates the murder of a young man outside of a liquor store. She uses all her interrogation skills and street smarts to find her suspect.

Dallas Homicide Detectives respond to a call about a body in the charred remains of a car. Digging into the victim's life uncovers a dangerous lifestyle with questionable friends. With each interview, a new piece of the puzzle is revealed and investigators take one step closer to the killer. In Memphis, Sergeant Tony Mullins and his team find themselves crossing state lines into neighboring Mississippi in their hunt for the person responsible for a home invasion that left one man dead.

In Memphis, Sergeant Mitch Oliver and his team respond to the murder of a man shot in his car while parked at a local mini market. In order to track down their shooter, detectives must rely on witnesses who sometimes hide more than they reveal. And in Phoenix, Detective Rosenthal is investigating the case of young man shot dead and left in the parking lot of a local bar. His biggest lead is the bar's surveillance tape. It could reveal who the victim was with the night he was killed.

In Miami, Detectives Emiliano Tamayo and Ervens Ford find a young woman shot dead in a convenience store. The store's surveillance footage reveals she may have been an innocent victim. Another man was the target. They need to find him before it's too late. Across town, fellow Miami Detectives Fernando Bosch and Rick Martinez are investigating the murder of a man shot dead on the street in the middle of the day. The victim's girlfriend was there and may know the identity of the killer.

At a gruesome crime scene in Dallas, TX, Detective Rick Duggan finds a badly decomposed body. To solve the case, detectives delve into the victim's past leading them on a trail lined with love and deceit. In Memphis, a dead body mysteriously dumped in an empty field has Detective Tim Helldorfer and his team scrambling for leads.

On a rain-soaked Memphis morning, Sgts. Tony Mullins and Mitch Oliver respond to a drive-by shooting, and learn that the victim is an innocent bystander. The man who says he was the intended target lead Mullins and Oliver on a manhunt for two brothers alleged to be the driver and the shooter. And in Dallas, when a man is shot to death in a van, Det. Dale Lundberg must untangle a web of conflicting stories about the man's identity to try to find his killer.

In Dallas, a young woman is found stabbed, beaten, and burned on a bed. The victim's 12-year-old niece and her mother are missing. Lead Detective Dale Lundberg soon discovers that this murder is extremely personal. In Memphis, Sgt. Mitch Oliver is investigating the homicide of a pool hustler found dead in a seedy motel room. The victim's car is nowhere to be found. Oliver hopes if he finds the car, he'll find his suspect.

A Memphis motel turns into a war zone when a gunfight leaves two men dead and another critically injured. Sgt. WD Merritt and the homicide team spring into action to find their shooter. In Kansas City, homicide Det. Everett Babcock leads the investigation into the shooting death of a two-year-old baby. To Babcock's surprise, an eight-year-old witness leads police on a nationwide manhunt.

Miami homicide detective Freddy Ponce is called to the brutal beating death of a homeless man. After finding what he believes is the suspect, Ponce's case takes an unexpected turn. In Kansas, a grandmother is found stabbed to death in her kitchen. Detective Ray Lenoir hunts down several potential leads, but it is the forensic evidence that finally reveals their suspect.

In Memphis, a gas station clerk is shot in an armed robbery. The clerk hits the store's panic button, locking his killer inside. Moments later, the clerk dies from his wounds. When Sgt. Kevin Lundy arrives on the scene, the store is sealed, with no way out, and the killer is gone. The team must track down a killer who seems to have disappeared into thin air. In Miami, Det. Rolly Garcia is investigating the murder of a nine-year-old girl who was killed while playing outside her house. The detectives believe that she was caught in a shootout between two men. They must rely on witnesses among the outraged members of the community to point them toward their suspects.

Miami Detective Carlos Castellanos and Sgt. Jose "Pepi" Granado are working the murder of a 54-year old tourist. As they hit the streets to track down the killer, they learn the victim was in town for more than the Miami sunshine: it's his son's 17th birthday. And in Memphis, a high school dance turns deadly when shots ring out. Sgt. Kevin Lundy must figure out who shot at a car outside the school, leaving one teen near death and another dead at the scene.

In Dallas, a woman is shot in while sitting in her car. Detective Eddie Ibarra and the homicide team focus in on two suspects swept up in a robbery investigation, and the pieces of the murder mystery begin to fall into place. In Detroit, a young woman and her daughter are shot dead in their apartment. Detective Ernie Wilson immediately gets the name of the shooter, but finding him is a game of cat and mouse.

In Kansas City, Missouri, a young man is found dead in the middle of an apartment complex. With no leads or witnesses, Detective Ed Begley is hoping the victim's cell phone can help him find the killer. In Memphis, a case gets personal for Sgt. Caroline Mason when a woman is killed in the neighborhood where she grew up.

In Dallas, detectives are working a shooting that left a 26-year-old woman dead, when a mysterious caller gives them a one word nickname--"Mississippi." In Miami, an elderly man is found duct-taped and beaten to death outside his house as his wife of forty years is asleep inside. Detectives have to find out whether the murder is a simple robbery, or a twisted act of retribution.