11-year-old Ben, Gwen, and friends go on the adventure of a lifetime in their own backyard.

Khyber, aided by a booger-like Slimebiote named Skurd, attacks Ben & co, but the tables turn when Skurd gloms onto Ben!

Ben and Rook join Kai Green on a perilous alien relic hunt through South America.

Charmcaster traps Gwendolyn in Ledgerdomain to exact her revenge once and for all.

While Rook is stuck on graveyard shift at Plumber HQ, his sensei Kundo returns as a cyborg to purge the galaxy of technological influence.

Ben finally manages to rid himself of Skurd... just when he needs the Slime-Biot most.

Ben fights for his wife on an alien reality show.

The Time War races towards its dramatic conclusion, with the fate of the entire universe and everything in it since the very beginning of time resting in the hands of Ben 10!

Ben and Rook follow Maltruant through the time stream. Ben has an adventure with George Washington, in 1773, fighting Maltruant and Vilgax. After defeating Vilgax, Ben and Rook chase Maltruant in the time stream to the beginning of time itself onto the starship of the Contemelia (the creators of the Annihilaarg) where Maltruant attempts to create a universe of his own using his own Anihilaarg. In a climactic battle, at the beginning of time Ben nearly dies trying to stop Maltruant from building his own universe but then it is revealed that the Omnitrix has a fail-safe to prevent its keeper from dying.