시즌 정규 출연진 8

1. 

   Noah Wyle

   John Carter

2. 

   Goran Visnjic

   Luka Kovač

3. 

   Maura Tierney

   Abby Lockhart

4. 

   Mekhi Phifer

   Greg Pratt

5. 

   Sherry Stringfield

   Susan Lewis

6. 

   Alex Kingston

   Elizabeth Corday

7. 

   Laura Innes

   Kerry Weaver

8. 

   Ming-Na Wen

   Jing-Mei Chen

특별출연 38

1. 

   Parminder Nagra

   Neela Rasgotra

2. 

   Linda Cardellini

   Samantha Taggart

3. 

   Scott Grimes

   Archie Morris

4. 

   Sharif Atkins

   Michael Gallant

5. 

   Paul McCrane

   Robert Romano

6. 

   Reiner Schöne

   Mr. Garland

7. 

   Bellina Logan

   Kit

8. 

   Donal Logue

   Chuck Martin

9. 

   Liza del Mundo

   Severa

10. 

    Michael Gregory

    Westbrook

11. 

    Troy Evans

    Frank Martin

12. 

    Amy Pietz

    Pregnant HIV+ Woman

13. 

    Oliver Davis

    Alex

14. 

    John Aylward

    Donald Anspaugh

15. 

    Glenn Howerton

    Nick Cooper

16. 

    Craig Ricci Shaynak

    Fritz

17. 

    Laura Cerón

    Chuny Marquez

18. 

    Lyn Alicia Henderson

    Pamela Olbes

19. 

    Amy Aquino

    Janet Coburn

20. 

    Lily Mariye

    Lily Jarvik

21. 

    Montae Russell

    Dwight Zadro

22. 

    Rossif Sutherland

    Lester Kertzenstein

23. 

    Emily Wagner

    Pickman

24. 

    Thandiwe Newton

    Makemba 'Kem' Likasu

25. 

    Eugene Butler

    Dr. Hewitt

26. 

    Sean Douglas

    Firefighter

27. 

    Destiny Edmond

    Judy

28. Seraina Jaqueline

    Berta

29. Marcia Jeffries

    Mrs. Marshall

30. 

    Asante Jones

    Workman #1

31. 

    Kevin Kane

    Jay

32. Tane Kawasaki

    Nurse Claire

33. Conrad Lindsay

    Tech Mel

34. 

    Jayden Lund

    Workman #2

35. Bill H. McKenzie

    Lee

36. 

    Julia Vera

    Reina

37. Sybyl Walker

    Flight Nurse Fran

38. 

    Ruth Zalduondo

    Radiologist

제작진 2