When a torrential rainstorm pounds Chicago, patients deluge the emergency room while Weaver speeds to an accident site. There, she finds a pregnant woman, Vicki lying injured inside a wrecked ambulance while live power lines spark. Fourth-year student Michael Gallant makes a dangerous decision in order to help.

Peter Benton continues his court fight against Reese's stepfather, Roger, who seems to have the upper hand. When a woman is accidentally shot during a gas station robbery, Dr. Corday tries to convince the husband to let them harvest her organs. A 15 year old boxer is brought in with a head trauma after sparring with his older brother. Newlyweds are having trouble when she constantly breaks out in a rash; Carter thinks he knows the cause.

Benton commits perjury on the witness stand in order to gain custody of Reese. When Romano refuses to give him a more even schedule, Peter resigns and seeks a job at the clinic where Cleo is newly employed. Benton is granted custody of Reese and he and Cleo decide to move to the suburbs together. Meanwhile, Carter's father visits for Christmas with the news that he's getting divorced, Weaver and Sandy Lopez finally go on a date, and Abby catches Nicole in the maternity ward, recovering from an abortion.

Abby helps a distraught boy whose mother died of a stroke; a man with schizophrenia, who once stabbed Carter and killed a doctor checks into the ER.

An injured and condemned murderer wants to die in the ER rather than await execution; Abby advises a neighbor to seek shelter from her abusive husband.

Drs. Corday and Greene are awkward when working together in the ER. Dr. Weaver treats victims of an intense fire that may take the life of a dear friend.

Carter confronta Abby sobre o seu problema com a bebida, por causa de uma carta de Mark; Kerry faz uma avaliação sobre a sua saúde; um acidente de carro revela um segredo sobre um jovem paciente de Lewis; e Pratt fica sabendo aonde passará o seu estágio.

Kerry espalha as boas novas, enquanto Abby fica sabendo que seu irmão deixou o exército; Kovaca satisfaz os seus instintos; Corday e Nathan chegam a um impasse sobre a sua carreira; e Chen ajuda um paciente Chinês que está sendo explorado por seu patrão.

Luka paga o preço pelo erro de diagnóstico que deixou um paciente com lesão cerebral; Carter se intromete na vida de Pratt quando ele é pego com uma arma; e Lewis quer que o departamento psiquiátrico preste atenção à depressão de um de seus pacientes.

Com a ajuda de Carter, Abby continua a procurar por seu irmão; Enquanto isso, o Kovac volta ao trabalho e lida com um caso de overdose; Pratt cava um buraco ainda maior com Chen, durante o seu trabalho com os paramédicos.

Abby and Neela are assigned to a month-long rotation in the neonatal intensive care unit where they experience emotional roller coasters while caring for the sick infants.

Weaver rushes to the aid of her female life partner, Sandy Lopez, when the firefighter is severely injured while working and must now battle for her life. Frightened Weaver whispers hope to Sandy by reminding the victim of their newborn child.