Lizzie tries out for cheerleader but doesn't do very well. Later that night she and Miranda chat online. Lizzie jokes that Kate made the squad because she stuffs her bra. Miranda accidentally sends out the message to everyone on the class roster. The next day at school Kate is furious about the taunting she's receiving and confronts Lizzie and Miranda, demanding to know who is responsible. Lizzie stutters and stammers for a few moments, then Miranda says that she did it. Kate promises to make her life miserable, and a war of dirty tricks breaks out between the two. Miranda tells Lizzie that she took the blame because Lizzie can't handle conflict. Lizzie feels guilty as the war between Miranda and Kate escalates. Finally Lizzie works up the nerve to take responsibilty for the message and she stands up to Kate. Also, Matt brings home a lizard for a school project and names it Lizzie, much to his sister's annoyance. While Mr. and Mrs. McGuire are supposed to be watching the lizard, it die

Lizzie and friends are frustrated--the only candidates for school president are super-popular cheerleader Claire Miller and oddball Larry Tudgeman, who promises to eat a worm for every vote he gets. Gordo encourages Lizzie to run as a ""normal"" candidate and Miranda seconds the motion. Lizzie agrees to do it. Gordo is her gung-ho campaign manager as she runs on a ""voice of the people"" platform. Lizzie starts to gain confidence, even enough to tell off Claire and Kate. Gordo thinks she should schmooze the ""second-tier"" popular kids in the drama club, so Lizzie puts on her shades and black leather and tries to get in good with them. Miranda is annoyed that Lizzie is blowing off the less popular kids and groups to hang with the drama club. Lizzie starts to develop a prima donna attitude and now Gordo has to agree that he has helped create a monster in candidate Lizzie.

Lizzie and Miranda note that when a girl gets her first bra, her personality somehow seems to change. They decide they are ready for their first, and hatch a plan to get Lizzie's mom to take them to the mall where they will shop for ""school supplies."" Lizzie is a terrible liar, though, and blurts out the real reason for the trip. Mom is overjoyed to help the girls out, but she embarrasses them as they are shopping. Lizzie is very harsh with her mother, telling her that she and Miranda are old enough to do their own shopping and to leave them alone. The girls face further embarrassment when they run into Kate, Claire, and their English teacher Mr. Coppersmith. They also find that they don't know what to look for.

Gordo, always the nonconformist, has a new passion: 1950s & '60s Las Vegas lounge culture, as epitomized by Frank Sinatra and the ""Rat Pack."" Lizzie and Miranda don't care for it, but they buy Gordo a Rat Pack CD. Ethan Craft listens to it on the bus and, surprisingly, likes it, which makes the girls reconsider their opinion. Soon they are dressing in fashions of the time. Gordo thinks it's cool that they like it, but hopes that his new interest won't become the latest passing fad at school. But that looks like exactly what is happening as Ethan soon has all the guys wearing hats like Sinatra and listening to the music. Even Kate is admiring the girls for being in first on the new trend and actually asks for their advice on what to do!

Lizzie and Miranda feel neglected, when Gordo spends more time with his new girlfriend, Brooke. They are unable to come to terms with the fact that Gordo has a girlfriend now and he is drifting away from their group. Meanwhile, Matt learns about "percentages" from his father and starts accepting bets from his friends, but he eventually lands in trouble when his mother finds out about this.

Hoping to win a trip to Miami, Lizzie, Miranda and Gordo team up to enter the school's ""Fact-athlon."" Their rival team consists of Kate Sanders, Larry Tudgeman and Claire Miller. But things start to look a little bleak when the faculty advisor Lizzie and company chose is replaced by substitute teacher Mr. Dig. But to their surprise, Mr. Dig manages to turn studying into something fun and interesting with his unusual approaches. By the time the competition starts, Lizzie's team is confident while Kate, Larry and Claire are feeling the pressure. But Kate's team beats Lizzie's team badly when there are too many questions about dates and names rather than ""how and why"" problems. Kate and her teammates gloat over their win and Mr. Dig is ready to leave his job at the school because he thinks he let the team down, But Lizzie, Gordo and Miranda convince him they they actually did learn a lot and that they had a good time doing it.

Gordo and Miranda visit Lizzie after she was out sick and bring her some scary news--in social studies class she has to pair up on a project with---KATE!! Lizzie reacts hysterically. She tries to get out of going to class the next day but her parents make her go. Kate is mad about working with Lizzie also, but she comes by the McGuire house to work on their project, cooking a Latvian dish called an Alexander Tort (a raspberry pastry ). At first the two are hostile to each other, but eventually they have a laugh or two and begin to recall the days when they were friends. Jo McGuire sees them enjoying themselves and tells the girls it seems like old times. Suddenly the girls stop being so friendly, then Kate excuses herself and leaves.

At school Miranda and Gordo ask Lizzie how it went with Kate, expecting the worst. Lizzie says it wasn't so bad. In fact, the two are going to the Digital Bean to do work on a high-speed computer. When they get there, Kate and Lizzie are working fine, but

Gordo has his camera and is filming Lizzie and Miranda in the school cafeteria. He forgets the camera when they leave, and when he goes back for it, he finds it was running the whole time. When the friends view the footage, they see Kate telling Claire a big secret--she's fourteen, a year older than the other seventh graders, because she was held back in kindergarten! This gives Gordo an idea. He sets up several hidden cameras around the school which catch lots of embarrassing moments on tape. Gordo plans to make a movie and enter it in a local competition, hoping to prove with it that even the popular kids have things to be embarrassed about.

When Kate dislocates her shoulder during cheerleading practice, Claire usurps Kate's position as captain.

Miffed with her parents for not raising her allowance, Lizzie gets her first job as a busboy at the Digital Bean.

Lizzie starts a column on her school's website, but soon finds it difficult to handle when her good intentions backfire.

Gordo uses his new credit card to fund his newest movie. Lizzie warns him about his spending limit, which leads to a fight between the two.