Diego decides that if Jesse wants Roy he won't stand in the way. So he goes to Roy's to tell him, but he catches Roy with another woman. He tries to tell Jesse but she won't listen, that is until Junior finally speaks and tells her it's true. She throws Roy out.

Although they have split up, Jesse turns up for a date with Diego that they arranged long before, only to find him about to go out with his new girlfriend. Jesse deals with it by acting it out her fantasies of a forties film noir.

Diego feels that Gwen is becoming increasingly clingy, but Jesse thinks she is just being nice, until Gwen transforms herself into a Jesse look-alike. John Warner Sr. dates an old friend, Mary Anne that he meets up with after thirty years.

A flu epidemic breaks out at the center where Jesse works. Carrie gets mad at Jesse for calling a monkey at the zoo stupid. Linda fears that Little John is becoming a geek.