When Shauna takes the office to the hottest nightclub in town, Mindy meets an unlikely potential suitor named Josh, who works as a lawyer for the New York Knicks. Meanwhile, Jeremy attempts to hit on a bride-to-be, and Morgan unexpectedly makes some extra cash as the club's bathroom attendant.

Danny gets caught sneaking out the office supply of painkillers for his troublemaker childhood friend Stevie who has instant chemistry with Mindy. Meanwhile, Mindy is in for a shock when Heather, Josh's ex-girlfriend who ruined Mindy's Christmas party, shows up at her doorstep to ask for her blessing to move into her apartment building. Mindy says yes, but immediately begins to plot ways to ruin Heather's rental application.

After returning from Haiti, Casey has an identity crisis and thinks being a disc jockey might be his new calling. When Mindy and the office go to a music festival for their “work retreat” to see Casey perform, the substance-filled surroundings lead to a series of disasters. Meanwhile, back in New York, Jeremy hires a new doctor, whom Mindy doesn’t particularly like after he saves the day during an emergency delivery.

Tax troubles inspire Mindy tries to rekindle a phony relationship with Cliff.

Danny is upset with Mindy’s horrible eating habits and decides to make a deal with her that he will stop smoking if she stops eating poorly. Meanwhile, Jeremy struggles to fill Peter’s spot at the practice.

Danny and a very pregnant Mindy cannot agree on a birthing plan, but these ob-gyns are reminded that some things are totally out of their control.

Mindy tends to her first pregnant patient at her new fertility clinic, but is suspicious that Danny may be trying to get her pregnant again.

Mindy reflects on her first day at Schulman and Associates to see just how much her relationship with Danny has changed in the last few years.

Mindy and Jody host a group of wild college girls, in town for spring break to get their eggs frozen. When Mindy gets distracted by a romantic night with Danny, the girls wreak havoc on New York City.

Mindy goes on a date with an Indian guy who questions her Indian heritage. hurt by this, Mindy starts hanging out with more Indian people. Jody and Morgan fight over the same girl, who has a shocking secret.

While Mindy struggles to take care of a sick Leo, Shulman & Associates is rocked by a nurses’ strike led by Ben, a handsome male nurse. Meanwhile, Jody tries to sell the upstairs apartment and Brendan Deslaurier comes to Mindy seeking help.

Still reeling from her breakup with Ben, Mindy finds herself living the same day over and over again, and realizes that the only way to break the spell is to make things right with Ben.

Mindy turns to her ex, Cliff, to help navigate her messy divorce. Peter returns to town to help pull Mindy out of her slump with an epic office karaoke party.

Mindy and Danny can't agree on the best way to care for an ailing Annette. Meanwhile, Anna throws a disastrous bridal-slash-baby shower for Tamra, where Colette has a heated confrontation with Jody.

Mindy’s fertility practice is in danger and Annette’s upcoming surgery looms large. While Mindy and Danny wait for word on the surgery, Mindy attends Morgan and Tamra’s dream wedding, where she and the rest of the Shulman gang try to find their own happy endings.