Skye collapses the morning after the “Cult” fan party, suffering a serious reaction to the drug she was slipped. The doctors urge Jeff to locate a sample of the drug so they can find a way to reverse its effects in order to save Skye’s life. Detective Sakelik arrives at the hospital but refuses to help. Jeff suspects that the drug might be hidden at her place so he takes matters into his own hands. Meanwhile, inside Skye’s hallucinogenic state, Billy, Kelly and Skye’s father Quentin encourage Skye to give up and stop searching for the truth.

Skye ha una brutta reazione alla droga che le è stata data durante una festa. I dottori richiedono un campione della droga usata per poterle salvare la vita. Nel frattempo, Sakelik si reca all'ospedale ma si rifiuta di aiutare Jeff.