When a call comes in from the Cook County jail, the squad steps into a volatile predicament and are tasked with trying to defuse an escalating situation. Shay remains hopeful about her baby dreams and Hermann's wife Cindy goes into labor with their fifth child. Meanwhile, Mills and Dawson face key decisions in their personal lives.

Herrmann tries to rescue a toddler from a structure fire. Mills discovers unexpected news.

Severide and Cruz find a child's remains inside a chimney while investigating a possible carbon monoxide leak inside a home. In other events, Casey braces for the worst in his run for alderman while Alderman Becks continues to bad mouth him to the press.

After responding to a time-sensitive rescue, Casey and Severide don't see eye to eye on the best course of action. Herrmann struggles to entertain his daughter on "bring your child to work day." Brett is joined by a surprise guest during a spa getaway, courtesy of Dawson, while Kidd's social life gets a boost.

Boden, Kidd and Severide work together to protect one of their own. At the Fire Academy, Herrmann meets an inspiring young man. Talk of the annual CFD Gala dominates the firehouse.

The big wedding day arrives and Firehouse 51 welcomes Casey back to celebrate the joyous occasion. Emma's plans to replace Violet come to a shocking end.

Firehouse 51 prepares for their semi-annual firehouse inspection. Brett fights to save her paramedicine program. Commander Martin Pearce asks Severide for a favor.

Truck and Squad clash after a tense call rescuing a doomsday prepper. Herrmann struggles with Cindy's diagnosis. Violet gives Brett and Gallo dating advice.

Firehouse 51 helps Herrmann put on a school fundraiser. Carver's troubled brother comes to town. A grateful citizen is determined to thank Brett and Severide for saving his life.

Kidd, Seager and Carver investigate a fire at the city stables. Kylie clashes with some of the firefighters over changes due to budget cuts. Herrmann struggles to keep it together as Cindy's condition worsens.

Mouch builds a classic firetruck model for the Deputy District Chief but needs some assistance from Gallo and Ritter. Brett and Violet encounter multiple victims with a strange set of symptoms. Cindy's chemotherapy results loom over the Herrmann family.