In a world where minds can be analysed for potential threats of crime and mental instability, Inspector Tsunemori Akane is sent to deal with her first case, along with fellow inspector Ginoza and a group of Enforcers, latent criminals hired by the police to work for them. Akane’s case deals with an insane man who has taken a woman hostage and raped her, holing himself up in a building inhabited by groups of the homeless.

The Sibyl System reveals itself to Akane and notes that she understands the necessity of the system, if not its justifiability. Makishima finds the professor who is responsible for the hyper-oats and murders him after finding the information he seeks, taking along the man's fingers and eyeballs as a measure against biometric security. Kogami arrives on the scene not long after and leaves a clue for the MWSPB in the man's airpipe. Meanwhile, Akane makes a deal with Sibyl: if the System withdraws the execution order for Kogami, she will capture Makishima alive. Thanks to her detective work, they quickly find Kogami's clue and understand what Makishima's up to.