Career-woman Trish Tait-MacDonald had no idea what she was in for when she had twins. Trying to stay on top of the house, the kids, and her job has left the state of the house in chaos.

Jennifer and Tyler Whitcher are overrun by their clutter. In an attempt to bury a tumultuous childhood that involved constant change, Jennifer Whitcher packs her present life with every comforting memory from the past.

A serious car accident years ago left Greg Cutchey unable to work outside his home. To make up for it, he has made a job out of selling and buying car parts online. The trouble is, he continually buys, but rarely sells.

Gail and Lester Neal live in a large, beautiful home with their six-year-old daughter Callia. They have stuffed their house so full that the three of them live, play, and sleep in just one room. The rest of the space is being used to store boxes.

Genevieve and Rod Wolfe recently moved in together, blending their two families of five children. But combining two households results in a lot of stuff, causing a lot of conflict.