At a Seattle cemetery, James Dickerson, a handsome 20-year-old, lurks outside the chapel during a college football player's funeral. After the mourners leave, James approaches the deceased's mother and sister. Calling himself "Ray Bell," he gains their trust by pretending to be a friend from college. He hugs the boy's grieving mother, savoring the hug in an unsettling way. That night, the mother visits the open grave one last time, when suddenly hands reach out of the grave, and drag the terrified woman inside.

A sudden hail storm sends students at Washington Polytech scrambling for cover. But one of the students, Lauren, wades through the downpour as the hail changes to rain. She approaches a teaching assistant who has taken cover in a breezeway. Lauren reaches for the woman's cigarette-and suddenly bursts into flames.

Peter Watts tells Catherine that Frank missed a routine homicide review with Yakima police that morning. Fearing the worst, Peter and Catherine access Frank's computer, looking for clues that would shed light on his disappearance. The pair uncover email correspondence between Frank (using the pseudonym "David Marx") and a Doctor Daniel Miller. Catherine tells Peter that five years ago, just before Frank collapsed, he would sometimes vanish for days at a time and check into hotels using the same pseudonym.

In the Brighton Beach area of New York City, a man named Yaponchik kills a Russian Elder by shooting him in the face with a 12 gauge pistol. It becomes the third such killing in which the perpetrator mutilated the body to prevent positive identification. Frank assists N.Y.P.D. Lieutenant McCormick, Yura Surova, from the Moscow Police Department, and undercover officer Andrei Medikov with the investigation. While inspecting the Elder's corpse, Frank notices an odd mark in the shape of a inverted "V." But he is unable, at first, to determine its meaning.

Frank aids in the search for a man who is supposedly carrying a highly contagious virus and discovers the secret behind the Human Genome Project.

Frank searches for a young man who disappeared in the Alaskan wilderness. In the Alaskan wilderness, the body of a young adult male, its face crushed beyond recognition, drifts down a river.

Frank searches for a female serial killer and her lover after the pair escape from prison.

Frank and Emma investigate a family of identical women who are apparently being killed off.

Frank and Emma investigate a mass grave that may have links to the Millennium Group.

Frank and Emma investigate a number of apparent drownings that occurred on dry land.

When a new family moves into town, Jordan is filled with the uneasy knowledge that the devil is near.

Emma and Frank investigate the mysterious biological research conducted by a former Millennium Group member who is dying from a mysterious disease.

Frank is held responsible for a man's death while Emma joins with the Millennium Group.