Alex was stabbed in the chest and Charlie sees her as ghost. Alex realizes she saw her father hang himself. Joel has issues with himself about Alex. Maggie end hers and Gavin's relationship. Alex end up in coma and remains ghost.

Alex's spirit shares an emotional journey with Charlie in the spirit world. Joel treats a drug addicts necrotic leg and strikes up a unlikely close bond to the patient. Dr. Sydney Katz begins her new job throwing Maggie off her game.

Alex is awake but still not back to her old self, and Dawn has given strict orders for her recovery plan. Meanwhile, Charlie and Joel square‐off over differing treatment options when two fused-together burn victims are brought into the ER, and Maggie finds herself in a whirlwind of emotions triggered from the fallout of her miscarriage.

Alex returns to work for the first time since her stabbing. She is introduced to her buddy colleague, as she returns. Joel ends up involved in a deadly situation at a local street clinic. Gavin shares a euphoric experience, with someone unlikely.

A mother and son are brought to the hospital after been involved in a car crash. Alex and Joel discover that the mother needs a transplant, and the son is adamant that he be involved in the operation. Rian and Maggie get caught up in a hazardous situation.

Alex, Maggie and Joel face a mystery; Charlie meets a patient with an usual link; an unexpected visitor has Zach questioning his abilities as a dad

Shahir and Alex attempt a radical surgery on an Alzheimer's patient; Tom discovers his mentor is keeping a secret; Charlie is torn between Dawn's wishes and the final requests of a dead con-man.

Alex and Charlie perform a double surgery on a teenage girl; Joel works at the clinic; Maggie must pull through when she is reunited with the Zarb family.

Alex and Joel are challenged with a marathon surgery. Charlie has a day off that's full of surprises. Dana, Zach and James are tested.

Celebrated neurosurgeon Thor MacLeod gives Alex an offer; Charlie deals with a fatigued spirit; Joel ends up in a fight at the clinic.

Charlie tries to treat two female MMA fighters; a fight between Dana and Molly ends up in the hospital; Dawn must save a woman's heart.

Two patients need the same heart; a patient has never-before-seen orthopaedic hardware; Dr. Maggie Lin feels the pressure of the upcoming boards.

Alex and Maggie perform an intricate procedure; Joel thinks his dad is hiding something; Charlie suspects foul-play when he sees a boy and his grandmother.

Alex asks for help in diagnosing a teacher with a mysterious illness; Charlie must explain his actions; Dawn must make a big decision.

Alex and Charlie try to save the life of a man on the run; a spirit won't leave Alex alone; Maggie and Zach try to help a couple; Joel and Shahir help a bride walk down the aisle.

Alex and Dana try to save a single mother's life; a hockey player's mobility is at stake; Charlie gets advice on winning back Alex; Sydney come clean

At an off-site army base, Joel and Zach get in a precarious situation; a hypothermia victim fights for the life; Alex, Maggie and Rian write their Surgical Boards.