When successful businessmen in Detroit are targeted by an anger-driven power-assertive Unsub, the BAU is called in to investigate.

The BAU is called to investigate a series of D.C. homicides where cryptic messages are found inside the mouths of each victim.

The BAU must determine what connects six people that each received a mysterious package in order to identify the Unsub. Simmons and his wife deal with their son's suspension from school.

Prentiss faces her past when the BAU is sent to investigate the murders of prominent businessmen, all of whom are missing their hearts. Also, Prentiss plans a romantic first date with Mendoza, but the evening is cut short by an urgent call from Rossi.

The BAU team investigates an UnSub with striking similarities to Rossi’s latest obsession, “The Chameleon,” a.k.a. Everett Lynch, who nearly killed him and then disappeared.

It has been a year since Rossi nearly died at the hands of Everett Lynch, a.k.a. “The Chameleon,” and he has developed some new theories, with inspiration from his former partner, Jason Gideon. The BAU team sets out on an epic hunt to capture Lynch.

The BAU hunts for the next connection to the serial killer network when they pursue a home invasion team. Alvez and Garcia convince Tyler Green to submit a cognitive interview to unlock his memories of Sicarius.

With Rossi in Voit’s clutches, he grapples with the limits of his technical know-how and mental strength. As the BAU tightens their grip on Voit, he reveals just how far he’s willing to take his deadly crusade.