Mannion investigates a series of robberies in which pharmaceuticals, mostly AIDS medications, were stolen; Temple worries about having to take a random drug test because of his failure to report that he used cocaine while undercover; Debreno reluctantly agrees to participate in a charity bachelor auction and is won by a sexy mayoral candidate (Kelly Rutherford).

Mannion tells Jenny McLure how his men arrested her brother while she is waiting for her final day. Jenny is dying from AIDS and Mannion makes sure her last days are filled with company and happiness. The cocaine found at Lester's apartment is missing, and Parras becomes of the main targets on the investigation on who switched the coke with sugar. Without the evidence they can't put Lester away, while matches from his pistol are coming from numerous murder scenes. Finally Chief Mannion finds the mole and sends Lester to jail, but unfortunately Jenny doesn't last to see the next morning: she passes away the day before Mannion's event to raise people's awareness on the danger and prevention of AIDS.