Teenager Leo entdeckt, dass sich im unterirdischen Labor seines Stiefvaters drei ungewöhnliche Kids verstecken. Adam, Bree und Chase haben das, was sich jeder insgeheim wünscht: übernatürliche Kräfte. Adam ist unglaublich stark, Bree ungeheuer schnell und Chase übernatürlich schlau. Die drei Teenie-Superhelden freunden sich mit Leo an und stellen sein Leben gehörig auf den Kopf.
Lab Rats is an American television sitcom that premiered on February 27, 2012 on Disney XD, which focuses on the life of Leo, whose mother marries billionaire genius Davenport. He meets Adam, Bree, and Chase, with whom he develops an immediate friendship. The series was created by Chris Peterson and Bryan Moore On January 15, 2011, Billy Unger, who plays Chase, stated that the series was originally called Billion Dollar Freshman. However, the pilot was re-shot, with the changing of the name to Lab Rats, and the addition of Bree, the only girl of the group. In the 19th episode a new character Marcus is entered in to the cast. On May 18, 2012, Lab Rats was renewed for a second season. On July 26, 2013, Disney XD renewed Lab Rats for a third season.