While being pursued by the Enforcers, Spider-Man has to protect Norman Osborn from the vengeful supervillain Vulture.

When a lab accident transforms Max Dillon into supervillain Electro, he demands that Dr. Martha Connors find a cure as Spider-Man works to stop him.

When. Dr. Curt Connors' attempt to regenerate a new arm accidentally transforms him into the Lizard, Peter, Martha, Eddie and Gwen search for a cure.

Following orders from Kingpin, Hammerhead hires Montana to steal a high-tech suit and, as the Shocker, destroy Spider-Man.

As Peter Parker and Harry Osborn try out for the football team, Spider-Man must face convict Flint Marko, newly transformed into the Sandman in order to destroy Spider-Man.

As Otto creates the Rhino as a new distraction for Spider-Man, Peter takes Aunt May's advice and asks Mary Jane Watson to the high school prom.

Peter and Mary Jane are a hit at the Fall Formal. Meanwhile, the Green Goblin's attack on Fisk Industries requires Spider-Man's intervention.

When the Green Goblin fuses Otto's robotic arms to his body, the newly created Doctor Octopus must find a new power source as Spider-Man pursues him.

Spider-Man faces off against the Green Goblin and Tombstone. Elsewhere, Col. John Jameson attempts to land a damaged space shuttle.

When the Sinister Six escape from prison with plans to take down Spider-Man, they nearly succeed. But Peter wakes up with no memory of the battle.

As he struggles with the alien symbiote, Spider-Man's origins are revealed.

Venom -- the merged entity consisting of Eddie Brock and the symbiote -- attacks Spider-Man through the people he loves most.