Season 0 of Mysteries at the Museum premiered on February 28, 2012.

Season 1 of Mysteries at the Museum premiered on November 2, 2010.

Season 2 of Mysteries at the Museum premiered on October 4, 2011.

Season 3 of Mysteries at the Museum premiered on April 17, 2012.

Season 4 of Mysteries at the Museum premiered on November 15, 2012.

Season 5 of Mysteries at the Museum premiered on August 14, 2013.

Season 6 of Mysteries at the Museum premiered on January 1, 2014.

Season 7 of Mysteries at the Museum premiered on September 12, 2014.

Season 8 of Mysteries at the Museum premiered on April 3, 2015.

Season 9 of Mysteries at the Museum premiered on October 2, 2015.

Season 10 of Mysteries at the Museum premiered on April 7, 2016.

Season 11 of Mysteries at the Museum premiered on July 1, 2016.

Season 12 of Mysteries at the Museum premiered on September 16, 2016.

Season 13 of Mysteries at the Museum premiered on November 4, 2016.

Season 14 of Mysteries at the Museum premiered on January 5, 2017.

Season 15 of Mysteries at the Museum premiered on April 6, 2017.

Season 16 of Mysteries at the Museum premiered on August 3, 2017.

Season 17 of Mysteries at the Museum premiered on November 2, 2017.

Season 18 of Mysteries at the Museum premiered on February 8, 2018.

Season 19 of Mysteries at the Museum premiered on April 5, 2018.

Season 20 of Mysteries at the Museum premiered on June 7, 2018.

Season 21 of Mysteries at the Museum premiered on September 5, 2018.

Season 22 of Mysteries at the Museum premiered on December 5, 2018.

Season 23 of Mysteries at the Museum premiered on January 6, 2019.