As Season 6 begins, Christian has news for Liz and the economic downturn has hit McNamara/Troy hard. But the boys might have found a lifesaver in Dr. Mike Hamoui (Mario Lopez), who's now in L.A. and has found a very profitable niche specialty. Meanwhile, Sean's relationship with Teddy Rowe (now played by Rose McGowan) has blossomed, and Matt, who's down on his luck, takes up mime.

Unable to sleep, Sean finds himself in an all-night diner, then in an ER; Liz goes after Christian's boat, leading him to offer Kimber a business deal; Sean and Christian remove tattoos from a teen obsessed with "the darker side of his personality."

Sean makes an important decision without consulting anyone; a morose Annie shows up in L.A. with a troubling medical condition; Christian gives Mike (Mario Lopez) tips on how to satisfy Kimber; and a new patient recognizes Teddy.

As Matt's crime spree catches up with him, Julia returns from New York to help in his recovery from surgery. Sean discovers devastating details about his marriage to Teddy. A new patient suffers from extreme separation anxiety.

When a newly married Erica threatens to take custody of Annie and Connor, Sean and Julia present a happy and united front to thwart her efforts. Christian bonds with a new patient as Mike reveals his future plans with Kimber.

Both Matt and Alexis Stone request unusual surgical procedures from Christian. Erica discovers the horrible truth about her new husband. After a lifetime of torment from her mother, Julia seeks revenge upon her.

A medical consultation with Liz's friend leads Christian to contemplate his relationship with Kimber. Sean begins to heal emotionally following an encounter with a perfection-seeking patient.

Christian's colossal financial debt leads him to deception. An unexpected visitor stirs insecurity within Christian and brings joy to Sean. Christian bonds with a young patient when he learns about his adoption.

Sean experiences an ethical and moral dilemma when McNamara/Troy is requested to perform a surgical procedure on a prison inmate. Kimber questions how far she will go to keep Christian when they receive life-changing news.