Z nového klienta se vyklube uprchlík před zákonem nebo možná kartelem, Christian ale jeho lest prokoukne. Využije toho a na neobvyklém případu vydělá více než desetinásobek běžné ceny. Později zkouší své štěstí u modelky...

Po shrnutí děje v předchozím dílu se dostáváme o 6 týdnů do budoucnosti na operační sál, kde Sean operuje poškozené poprsí. Poté se s Christianem setkává s novými pacienty, dvojčaty Mandi a Randi Danteovými, které už nechtějí vypadat stejně.

Po shrnutí předchozích dílů se dostáváme k pohovoru mezi Christianem a imitátorem Michaela Jacksona Diamondem o počtu jeho operací v minulosti, následuje jeho rozhovor se stálou klientkou Heddou Grubmanovou, která požaduje lepší prostěradla...

V úvodu přichází klientka, která natáčí filmy pro dospělé. Zjevně je poněkud naivní a potřebuje odstranit modřinu z pozadí. Sean upozorňuje, že mají 2 měsíce plno, ale Christian slibuje hned další čtvrtek (doufá, že to přinese další klientky z oboru).

An ex-lover returns and leads Christian to a sexaholics meeting while Sean and Julia deal with an unexpected pregnancy.

Someone is vandalizing Christian's possessions, and he attempts to find the culprit. A chemotherapy patient who is considering breast implants brings excitement to Sean's life, and Matt finds himself in a threesome with Vanessa and Riley.

Christian's difficulties with Kristin are exacerbated when his feelings for Julia are revealed. Jude is hired as an intern, to sexy and disastrous results. Matt is caught mid-threesome by Julia.

Sean and Jude's respective secrets are revealed, and Merril offers Christian an interesting trade: Kimber for a Lamborghini. Christian accepts, but Kimber discovers the truth and exacts a small revenge.

Sean and Christian learn that they have to take a test in order to continue practicing. Sean and Megan visit a doctor to learn that there is nothing they can do for her. Mrs. Grubman returns to get an operation on her and her fiancé. Christian passes his test, but Sean walks out. Megan commits suicide. Julia finds out about Sean's affair with Megan.

Ms. Caine wants an operation to get rid of her "cankles". Sean and Julia are still on the outs. Christian learns he's going to be a father. Julia steals Christian's brush to determine if he's the father of Matt. Sean and Grace learn that Ms. Caine has multiple personalities. Cara recovers and gets close with Matt and Henry. Henry develops feelings for her. Cara asks Matt to the prom. Henry tells Matt that he is going to confess to Cara what happened.

Sean and Christian are reunited with an old friend, Julia bonds with Sofia Lopez, and Christian and Gina clash over their differences in opinion concerning Gina's pregnancy.

Christian learns that Kimber and Merril are engaged. Escobar continues to have the surgeons do things for him. Liz is sent to Bermuda after being shot in the leg by one of Escobar's people. Sean goes to kill Escobar. Escobar makes a deal with Sean; a new face for their freedom. Christian learns, in the delivery room, that he is not the father of Gina's baby. Julia returns to get the paternity test she had done a while ago. The doctors do surgery on Escobar, and give him the face of a criminal even higher than Gallardo on the Most Wanted List - Armand Ortiz. Ortiz is arrested at the airport for bank robbing and killing a federal agent.