The culture of cocaine is deeply entrenched on Wall Street and some will pay more than its worth for the purest quality available. It’s a buyer’s market and dealers must compete to deliver first and close the sale, while keeping up with the changing Wall Street appetite. A new generation of brokers and traders are turning to a drug that keeps them performing at work. And police are coming down on a drug that they regard as Wall Street’s dirty little secret — which is quickly turning into an epidemic.

The relationship between the million-dollar hip-hop industry and the billion-dollar drug industry; rappers in Calif. use drug money to pay for their studio time.

Delving into the Los Angeles porn industry, where a reputation for illegal drugs is under more scrutiny than ever after a number of HIV scares are changing the toleration of narcotics on set.

Thousands of students head to Cancun, Mexico for Spring Break and some have only one thing on there mind: to get wasted.

Enterprising inmates in two jails with tough drug policies, one in Calif. and the other in N.J., still find ways to get drugs inside.

As trafficking drugs through the Caribbean increases in preference to the land route across the Mexican border, gangs in the Dominican Republic have become a key players in the transhipment of cocaine.

Follow Detroit’s dealers, cops and feds as they take on the city’s wild rave scene in the frantic 48 hours leading up to Halloween. Anarchy rules the Motor City: Around the notorious 8 Mile Road, street slingers stock up and look for new opportunities downtown. In the suburbs, middle-class dealers bring party drugs to raves.

When Pittsburgh police crack down on heroin, they inadvertently open the door for wannabe dealers that see a chance to muscle their way into the market with a killer brand.

The side effects of drug use can be disastrous, but the people living in the world of the living dead fight an epic battle.

The drug of choice in Silicon Valley is cocaine, but a cop crackdown is pushing dealers and their programmer clients to meth.

From the DEA and dealers to users and doctors, Grim Reaper explores the deadliest drugs across the globe.

Heroin on Staten Island is reaching epidemic proportions as dealers from New Jersey take advantage of a crackdown on prescription pills that's leaving teenagers desperate for a soporific high.

Follow the rise in demand for narcotics during Mardi Gras, Spring Break, Independence Day, and New Years Eve, through the eyes of dealers, law enforcement and users

Cocaine is Europe-bound and which means a white-knuckle ride along the Amazon, to the docks of Ghana and Nigeria and all the way to Amsterdam.

Arresting drug dealers is just the beginning for some in the drug game, as some inmates continue to do business behind bars.

Outlaw bikers fight cops and Chinese Triads to keep control of the crystal meth trade.

Meet the network of traffickers, runners and smugglers delivering meth to the masses in Austin. At the Tex-Mex border, officials do everything they can to cut off supply.

Marijuana is widespread amongst the student population in Boston and, with National Weed day on the horizon, dealers and students are gearing up.

Thai police battle an addiction epidemic as popularity of meth pill Yaba spins out of control. Dealers continue to find ways to dodge the authorities and keep profits rolling in.