A look at the fight against the country's most dangerous dealers and the biggest producers. From smuggling at JFK International Airport to cartel kingpins in Arizona, U.S law enforcement is fighting the global trade

After being rocked by a corruption scandal and a budget deficit in the range of 58 million dollars, the city's police department's staffing and morale are in bad shape. National Geographic follows an elite team of detectives who are trying to establish some control over the free for all drug market. Using their access to the dealers, users, and gang members at the heart of the problem NGC gives us a inside look at the drug infested city.

Washington, D.C., was once “Crack City” and the murder capital of the U.S. But an increased police presence following Sept. 11 made drugs scarce. In the neighborhoods of southeast D.C., one drug remained — PCP. And it's causing havoc. NGC goes inside the chaotic world of PCP where users think they're invincible and can be driven to insane acts of depravity. Visit the emergency room unit where doctors treat up to 80 psychotic patients high on PCP each month.

Portland's progressive attitudes have made it a mecca for America's homeless and they're helping fund the deadliest drug market in the Pacific Northwest. Here, pushers prey on the young, handing them free sample bags of narcotics to turn them into new customers. With thousands of Portland's youths succumbing to heroin's powerful allure, local police have made it their No. 1 priority to disrupt the flow into the city by smashing the local distribution networks.

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Molly, a powdered form of the drug MDMA, is exploding in popularity across the United States. Formerly marketed in pill form as Ecstasy, Molly is a total rebrand. Marketed as purer, cleaner and “without the additives,” this powder has become the most fashionable new drug for young people. But as the consumer demand for Molly has exploded, the production of pure MDMA has struggled to keep up with supply. As a result new, dangerous chemicals are finding their way into the market.

The southwest border of the U.S. is the main gateway for illegal drugs, and Dallas, Texas, is often the first port of call for the Mexican cartel drug trade. In this episode, witness how the Mexican cartels have tainted Dallas by turning it into their command and control center for the trade of their narcotics. Buyers desperate to get a hold of the cartel's high-quality product flock to Dallas from all over the country, giving local dealers the chance to make big money

Baltimore, a once prosperous city, lost many of its jobs along with its steel mills. In return, the city developed one of the biggest heroin problems in the country. For many of those that remain amid the poverty and abandoned homes, the “Heroin Hustle” is the way of life. One strip of Pennsylvania Avenue alone is estimated to take in $10 million a year from heroin sales. With the business booming, the heroin market is expanding outward to the suburbs, and the authorities are struggling to cope.

Dominican drug networks tied directly to the Mexican cartel are distributing countless amounts of narcotics in the historic city of Boston, fueling a widespread epidemic that law enforcement and emergency services can hardly contain. The Dominican drug organizations are increasingly using Puerto Rican dealers as their middlemen to flood the city with heroin. The epidemic touches all communities, making Boston one of the leading cities for heroin distribution.

A journey through the daily lives of drug crews in New York, Atlanta and Portland.