The first season of Wizards of Waverly Place aired on Disney Channel from October 12, 2007 to August 31, 2008. The season introduces the Russo children, Alex, Justin, and Max Russo as they compete to become the leading wizard in their family. Maria Canals Barrera and David DeLuise co-star as their parents and Jennifer Stone co-stars as Alex's best friend, Harper Finkle

Guest stars and recurring cast include: Amanda Tepe as Monotone Woman, Skyler Samuels as Gigi Hollingsworth, Bill Chott as Mr. Laritate, Daryl Sabara as T.J. Taylor, Brian Kubach as Riley, Shane Lyons as Manny Kin, Eric Allan Kramer as Coach Gunderson, Chelsea Staub as Kari Langsdorf, Sara Paxton as Millie, Julie Brown as Ms Angela and Jeff Garlin as Uncle Kelbo.

I Russo sono una famiglia italo-messicana di maghi che vivono e gestiscono una paninoteca, la Waverly Sub Station, a Waverly Place, New York. Il padre di famiglia, Jerry Russo, è un ex mago, che dopo aver sposato una mortale, Theresa, è stato costretto a cedere i suoi poteri magici a suo fratello, Kelbo.