When convicted murderer August Tillman escapes from prison, Veteran U.S. Marshals Charlie DuChamp and Ray Zancanelli decide to take an unorthodox approach to fugitive apprehension by forming a special task force comprised of the three most elusive fugitives they have ever captured. Convicts Lloyd Lowery, Philomena Rotchcliffer and Shea Daniels agree to assist in the case in exchange for time off their sentences.

Xavier Price escapes from prison in the midst of a candlelight vigil outside the penitentiary. The Breakout Kings are immediately brought on the case to try and track him down. It turns out this violent criminal is a "collector," and has a history of kidnapping women, torturing them, and holding them captive in basements. Once the team learns he currently has a woman hidden away somewhere, the race is on to the find her before Virgil can harm her.

Theodore 'T-Bag' Bagwell, a sociopath with a prosthetic hand and a mean streak to go with it, makes a bloody escape from prison and sets out on a path of vengeance.

Joe, a convicted pedophile, disguises himself as a crewmember on a film shoot and makes a break for it. The team must not only catch him, but must be sure he doesn't commit any more crimes while on the loose. Their first lead sends them to the school where Joe worked as a counselor and where the six children are who he as accused of molesting. They also manage to track down Joe's estranged wife and children, whose lives have been seemingly destroyed by Joe's life-sentence in prison. Meanwhile, Erica is determined to see her six-year-old daughter on her birthday and Charlie's wife urges him to take her on a much-needed vacation.

The team tries to catch a ruthless woman convicted of murdering her husband by stabbing him 48 times, who escaped from prison on a school bus. It turns out the woman was tricking men into thinking she really cared for them so they would do what she wanted and help her escape. Charlie and Ray's special task force must catch her before she hurts more people -- and also make sure her 14-year-old son stays safe. Meanwhile, Lloyd's gambling debt increases and a scary Born Again inmate threatens his life if he doesn't come up with the money right away.

An escaped convict is out to bring down the prison system, all the pillars of organized government that he detests, and even a member of the team assigned to bring him to justice; Lloyd faces some difficult questions about where he came from.

An oversized inmate is poisoned and his coffin is used as a “Trojan Horse” for two inmates to escape the Cayuga Correctional Facility. One prisoner, out for revenge, brutally murders a prison guard, causing friction with the other prisoner, who only wants a big payday and to live in luxury. The murder also increases the urgency to catch the cons. Meanwhile, Ray dangles a tantalizing carrot in front of the team: between Erica, Shea, and Lloyd, whoever proves to be the most useful on this case will be the proud recipient of a tasty steak dinner.

A handsome, rich, and cunning jewel thief, Andre, escapes from prison leaving all the prison guards scratching their heads and he breaks out just in time to make the biggest score of his career. It’s up to the Breakout Kings to track him down and figure out just what he’s been plotting and stop him before its too late. Meanwhile, Shea and Erica plead with Ray to allow them to have conjugal visits.

A notorious contract killer escapes from the prison to carry out some unfinished business. As he is offing people left and right, the Breakout Kings must try to figure out the connection between his victims, catch him and lock him back up before he can kill again. The common thread between all of his victims was involvement in a tragic story involving the rape of a young female college student 5 years earlier, who’s father happens to be a guard at the prison from where he escaped.

A violent schizophrenic with the skills of an outdoor survivalist and a history of ritualistic killing is off his meds and on the hunt. His prey, Debbie Myers, is a beautiful, young television host. After killing an orderly, he escapes and the one thing on his mind is finding Debbie, taking her to a special place in the Adirondack Mountains and consummating their “love” through a bizarre and violent ceremony which will surely end up with Debbie being killed.

A shocking scene at a prison erupts when an 18 wheeler crashes into the prison wall and an armored car escapes from the back of the truck, with several convicted felons hiding inside. Our rag-tag team is quick to begin the hunt for the fugitives and they learn the escapees are being lead by Ronald Barnes, a Madoff-like man who is hated by all. The follow Barnes’ trail and eventually realize that his plans of helping his fellow cons reach freedom along with him were all a ruse to distract the authorities from tracking down Barnes himself. Barnes will kill anyone that gets in his way and the Breakout Kings must outsmart him before it’s too late.

Carmen Vega, the ruthless queen pin of a drug cartel, pulls off a violent and deadly escape while attending the funeral of her slain son. Her plan, get the family business back in order and hand over the keys to the kingdom to the heir apparent, her son Cesar. Carmen will stop at nothing, including killing a member of her team and even her own family, to put Cesar on the throne. The Breakout Kings seem to be one step behind Carmen at every turn and they smell a rat. Is there an informant within the team? Not only do the Breakout Kings need to catch Carmen to their month off, they also need Carmen to give up the location of where Shea’s girlfriend is being held hostage to save her life. Find the rat, catch Carmen and save a loved one, the Breakout Kings have their work cut out for them. In the end, they realize they really are a team and there’s no going back.