Danny and Jackie are assigned to protect a key witness in a Russian mob trial, but when an attempt is made on her life, they realize there is a leak on the task force. Meanwhile, Erin is offered a job as deputy mayor, which would have her working directly with her father.

A woman recants a domestic-abuse claim, but Danny and Jackie continue to investigate the situation. Soon they uncover the woman's secret affair with a powerful politician who's friends with Frank. Meanwhile, Linda returns to the workforce, causing chaos at home.

Danny arrives at a college campus to find a murdered student, who was thought to be dealing drugs. Meanwhile, Jamie has a life crisis when he reconnects with a former law school classmate and Erin must learn to give Nicky some freedom.

When two Wall Street brokers are killed in drug deals, Danny looks to question a wounded accomplice at the hospital but he is stopped by Linda, who won’t let Danny see him until after surgery. But when the accomplice dies during the procedure, Danny and Linda battle over the judgment call.

When an armed robbery ends with the death of a police officer, Frank makes it a mission for the NYPD to bring the suspect to justice. However, tensions run high in the Reagan household when Erin drops the charges and releases the suspect due to lack of evidence.

When an officer is accused of using excessive force on a suspect, Frank finds his department under scrutiny from the community and the mayor. Meanwhile, Danny and Baez investigate the murder of a Wall Street securities trader who was deep in debt due to a gambling addition.

Danny and Baez investigate a local bombing, but meet with tension and resistance from the community during the investigation. Meanwhile, Frank must deal with the political fallout when a man punches an officer who was overly aggressive in his questioning.

A kidnapping investigation brings back bad memories for Danny, who worked a similar case years ago; Frank and Inspector General Peterson butt heads.

Erin investigates a case involving a police officer accused of killing a suspect in custody; Jamie encourages Eddie to forgive her father.

Jamie stands up for a fellow officer, ostracized for testifying against their partner. Frank is given a difficult request by Boomer.

A woman who was held hostage resists pressing charges, but Danny and Baez want justice for her. Meanwhile, a high-profile NYPD fund-raiser uses a phony police vehicle to avoid traffic; and Jamie has the opportunity to be a technical adviser on a TV show.

After Emily Harrison tells Danny and Baez she's concerned her abusive ex-boyfriend will repeat his behavior with his new girlfriend, Emily becomes the prime suspect when he's murdered. Also, Eddie gets jealous when Jamie lets a young woman crash at his apartment, and Frank must decide how to discipline a sergeant after he fails to intercede during an armed robbery while off duty.

While investigating the murder of a gang leader, Danny and Baez learn the accused shooter is an ex-con who is romantically linked to his parole officer, who might be assisting in a cover up. Also, concerned the murder might spark further violence, Frank steps in to mediate but must deal with Mario Hunt, the rival gang leader who killed a police chief two years ago.

In the season finale, when Danny intercepts a shipment of several million dollars that was heading to a drug cartel in Mexico, he becomes a target when they come back for revenge. Also, Jamie works independently to track down a serial killer who preys on the elderly.

Erin’s trial against a notorious human trafficker is jeopardized when the presiding judge is mysteriously found dead. Danny and Baez are put on the case to investigate foul play. Meanwhile, Mayor Dutton opposes Frank’s public safety initiative, but City Council Speaker Regina Thomas devises a plan to help Frank bypass the mayor’s veto.

Danny and Baez join a narcotics task force to track a drug supplier; Baez comes into contact with drugs and gets an accidental overdose; Jamie and Eddie work to protect a rehabilitated sex offender; Frank forms an unlikely alliance with Mayor Dutton.

When a student is shot by a rival gang member in his high school courtyard, Danny and Baez try to get a grasp on the situation to prevent a reoccurrence, but the principal recklessly takes matters into his own hands. Also, Erin tries to help a friend who is mixed up in an illegal gambling ring; and Gov. Mendez tries to frame Frank after one of his top legislative aides is shot by an NYPD officer

Danny and Baez race to find a missing girl who will die within 72 hours without her heart medication. Also, Jamie and Eddie are on the wrong side of an investigation after engaging in a car chase, Frank, Garrett and Gormley investigate the rise in the settlement of lawsuits against cops, and Sean wins an essay contest and receives a medal from former New York City Mayor David Dinkins.

Gormley looks to Danny and Baez for help tracking down a former NYPD detective he believes may be a threat to Frank's safety. Erin navigates office politics when she chooses to reopen a closed case. Jamie is transferred to a new precinct with a lot of problems. Frank and Baker team up to investigate a complaint about an SVU detective.

It’s Reagan versus Reagan when Danny goes against Jamie’s direct order during a hostage negotiation. Also, Nicky asks Erin for help when her friend is in jeopardy of losing his scholarship because of a crime he didn’t commit, and Frank helps a distraught officer who accidentally shot an innocent girl.

Erin must convince Frank to back a new state police bill as part of a bargain she made with Governor Mendez. Also, Danny and Baez pursue the same perp twice after the DA’s office is unconvinced by their initial lineup, and Frank faces a challenge when a cop killer comes up for parole.

Frank and Erin are at odds when Frank learns the D.A.’s office keeps a list of “unreliable” cops. Also, Danny and Baez recruit retired mobster Vincent Rella to assist in an investigation, and Jamie participates in a decoy operation to take down a predator posing as a ride-share driver.

While Henry works as an investigative consultant for child services, he and Danny butt heads over a case involving a man who is volatile toward his wife. Frank is caught in the middle of an ongoing battle between the NYPD and the FDNY. Erin ponders a life-changing opportunity presented to her by Mayor Peter Chase. Jamie is suspicious about an investigation targeting Eddie's partner.

Danny and Baez work with Texas Ranger Waylon Gates when they are put on a case to find the Lone Star Killer. Also, after Eddie's partner, Officer James Addison, mistakenly shoots an undercover cop, internal affairs accuses Jamie of not supervising properly, and Frank speaks with Officer Addison about why he shouldn't turn in his shield.

Erin is conflicted by the weight of her authority in the sentencing of a man who is guilty of vehicular homicide; Danny and Baez pursue a rideshare rapist; Jamie and Eddie team up to aid a fellow officer when his partner is shot on the job.

The Reagans confront hard choices on the job when Frank deals with a police captain who's losing his grip over his precinct, and Danny faces backlash from the Baez and Internal Affairs over a tough call he made in the field.

Frank takes matters into his own hands to save Gormley's career when complaints against him become public knowledge; Danny and Baez learn to be allies when the transgender community comes under attack.

An illegal drug shipment arriving in New York City must be found before the narcotics flood the streets; Jamie helps a neighbor handle a gambling debt; Frank receives pushback from Mayor Chase over his handling of a brawl.

Frank contends with public outcry to defund the NYPD School Safety Division, after a physical altercation between a school officer and a student goes viral; Danny and Baez help a father track down his missing ex-wife and daughter.

Danny and Baez investigate a series of violent robberies targeting luxury timepieces; Erin is conflicted about criminally charging a potentially innocent man; Frank is forced to reopen a case in which the officer involved was acquitted.

Danny partners with Texas Ranger Waylon Gates to deliver an infamous drug cartel boss to arraignment, but the mission becomes complicated when the criminal threatens to harm the Reagans; Erin takes on a highly contentious assault case.

Jamie partners with the FDNY to find the arsonist responsible for a massive fire at an NYPD evidence storage facility; Eddie asks Frank to put her on modified duty following her divisive arrest of an anti-cop protestor at a rally.