Manny Coto talks about the construction of the fourth season as a series of mini story arcs that would tie more directly into the Star Trek canon. Brannon Braga was burned out on Star Trek and was ready to move on. Mike Sussman recollects the brainstorming with Manny Coto in between the third and fourth season. André Bormanis recalls that Manny Coto really wanted to do more about the creation of the Federation. Garfield & Judith Reeves-Stevens spoke to their time as writers brought in by Manny Coto.

Larry Nemecek notes that Enterprise had to get good ratings. He notes that the episodes where good, but the ratings were not that good. Judith & Garfield Reeves-Stevens mused about the signs that the show was ending. Mike Sussman noted that the budget for season four had been reduced. He notes that was mitigated by amortizing the cost across multipart episodes. This gave rise to three episodes on Vulcan, three about the Augments, three about the Andorians & the Romulans, two about the mirror universe and the final arc about the xenophobic movement on Earth at the time the precursor to the Federation was being negotiated. Manny Coto talks about a potential of William Shatner being on Enterprise via something involving the Mirror Universe. Mike and Denise Okuda noted how wonderful the original series sets (reproduced for the Mirror Universe two-parter) are. Manny Coto notes that he wanted to do more Gorns and Tholians. Several cast members comment on season four.

The effect of UPN on the end of Enterprise. Several cast members and crew comment on the "let down" that comes with the end of the show. Jolene Blalock comments on the last episode and her disappointment with it. Conner Trinneer was happy with it. Manny Coto muses about what he would have liked to explored.