After the events of "Rigby's Graduation Day Special" the Park guys and Eileen must formulate a plan to survive in space and how to live in it.

The crew have an encounter with "brobots" whose purpose is to serve others, but Mordecai and Rigby are suspicious of them.

After learning their true mission in space, the crew is excited to make history, but Benson still wants to return home.

Mordecai and Rigby volunteer to rescue a scientist's ex-husband in exchange for space creds so they can buy hover shoes.

Chance Sureshot loses his wallet and is enclosed in a robot's bubble until he can pay for his food. In order to free him, Mordecai, Rigby, Toothpick Sally and Recap Robot must travel to the Mantis Planet to get it back.

In order to get back at the Bush Station, Colonel Rawls hires Muscle Man to prank them.

When Pops continues to have nightmares of an extraterrestrial creature asking for his address, the gang tries to help him.

Mordecai and Rigby must stop an evil brain after Rigby releases it from a cage.

After getting dumped by Pam, Benson goes looking for French Fries ingredients with a female asteroid named Roxy.

Colonel Rawls puts Rigby through safety training by pairing him up with the unbearable Spacey McSpaceTree.

Mordecai and Rigby must go to court after accidentally creating a barrage of sounds on a planet completely inhabited by sensitive ears.

Mordecai and Rigby go to see Fist Pump perform at the Tree Station, but get stuck in a space elevator whilst traveling to the top.

Mordecai and Rigby have to beat the Space Bush station in a dangerous race.

Mordecai and Rigby try to avoid spoilers of their favorite show, but Benson wants to spoil it to get revenge on them for forgetting to vacuum the house.

A mysterious new enemy, Anti-Pops, is after Pops forcing everyone on the Space Tree Station to evacuate.

After escaping Anti-Pops, the gang make a quick stop to buy new beds only to encounter a bounty hunter who is after Pops.

Mordecai and Rigby's butts get swapped after playing with a teleportation machine. Over time, the swapping spreads to other features, so they enlist Muscle Man for help.

The Park crew encounter the Alpha Dome, the first dome sent into space. When the crew go to investigate they find that its inhabitants believe that it is 1690.

The guys gather in the house on the Dome and tell scary Halloween stories just like ol’ times, only this Halloween, the stories have an extra terrifying, science fiction twist. (1/2)

The gang must travel to an ancient VCR that will play a VHS tape, made of ice, so that they can learn Pops' origins.

Earl, an ancient sensei, begins training Pops for his fight with Anti-Pops, but Pops is not sure if he can or should go along with it.

Earl begins training Pops through the technique of the training montage which allows trainers to bend space and time while leveling up. Mordecai and Rigby use one of their songs to help Pops and end up trapping the Park crew in a montage.

The guys celebrate their first Christmas in space by opening presents, eating peppermint bark and telling Christmas stories. Benson wants the stories to be more Christmasy but the guys keep adding scary elements, which infuriate their boss. (1/2)

The guys celebrate their first Christmas in space by opening presents, eating peppermint bark and telling Christmas stories. Benson wants the stories to be more Christmasy but the guys keep adding scary elements, which infuriate their boss. (2/2)

Despite all of his training, Pops still does not want to fight, so he sets up a meeting with Anti-Pops to settle things peacefully.

The crew arrive on Planet Nielsen where they are reunited with the Guardians of Obsolete Formats and meet the Seer who has been watching them since the very beginning.

Before arriving at Lolliland, Pops becomes despondent due to his approaching battle. The crew then try to cheer him up by recording their memories.

The crew arrive at Lolliland early, so they set up traps for Anti-Pops. Things seem to go off smoothly, but Anti-Pops is unfazed by their futile attempts.

Allies from both sides rally together for the epic fight. However, Pops and Anti-Pops are once again at a stalemate. Mordecai and Rigby are forced to jump between the two factions.

Mordecai and Rigby relive the first episode, but soon realize that they need to help Pops. Pops realizes that he must reach out to Anti-Pops and finally saves the universe at the cost of his life. The entire park crew return home to their friends and family where they are seen growing up and moving on to better lives. 25 years later, the entire crew return and Mordecai and Rigby reflect on Pops' sacrifice. Regular Show ends with Pops watching the series on VHS and uttering one final "Jolly Good Show".