The show explores the mystery of whether or not Adolph Hitler really committed suicide as Allied Forces invaded Berlin, or managed to escape the country since no body was ever produced. Forensic investigators examine an alleged piece of Hitler's skull provided by the Russians to determine if it really belongs to the dictator.

The show explores the mysteries of the Bermuda Triangle to find out what could be disorienting airplane pilots and to search near the Bahamas for the wreckage of the first reported aircraft to go missing.

The San Francisco Bay Area was terrorized by a serial killer known as Zodiac who angered the residents and taunted the police. With the use of DNA technology, investigators were able to identify a new suspect in the crime spree.

Using the latest in sonar and underwater exploration technology, investigators dive to various submerged ruins, including Bimini Road in the Bahamas, with the hope that one of them could possibly be the remains of the legendary city of Atlantis.

Shadowed by military security, investigators trek into the Nevada desert and use the latest in surveillance technology to monitor supposed UFO activity at the most classified U.S. government installation, Area 51.

Investigators look into reports of Nazi SS personnel, such as Josef Mengele and Martin Bormann, who are believed to have escaped justice after World War II through the help of a secret organization known as ODESSA and sympathetic members of the Catholic Church. They reportedly fled to Paraguay where they plotted to reestablish their sinister regime.

A look at the history of Alcatraz Island, located in the middle of San Francisco Bay and once a federal prison which opened in 1934. It was deemed inescapable, but in 1962, three inmates managed to get off the island, but their fates have remained a mystery. Investigators try to determine if the men could have survived the frigid waters and make it to shore.

Over a century ago, London was terrorized by one of the earliest documented serial killer cases, Jack the Ripper, who slaughtered prostitutes in the Whitechapel district. Unsolved to this day, authorities dismissed the killer as a local madman, but investigators are now looking into surprising new evidence that theorizes the killer could possibly have been a woman, or not English, but an American.

A team is sent to investigate Stonehenge – the mysterious ring of standing stones in Wiltshire, England – to test a new theory that sound reverberation was used to induce trance-like states among the ancient worshipers who used the stones for religious and sacrificial rituals.