While Julian makes Brooke a surprising offer, Lucas takes Nathan and Jamie to an important place from his past. Meanwhile, Peyton prepares for the future; Sam and Jack go up against the principal who fired Haley; and Skills and Mouth go on a road trip to help Mouth forget Millie.

The parents of Tree Hill face difficult challenges: Lucas finds himself fighting to stay calm when Peyton's pregnancy faces further problems, Nathan and Haley clash over the decision to pull Jamie out of school, and Victoria returns to tempt Brooke back into the business. Meanwhile, Mouth continues to mend his relationship with Millie.

Nathan and Haley both face their dreams as he questions his ambition to play in the NBA and she receives an offer from Nick Lachey. Meanwhile, Brooke learns something that could change Sam's life forever, Jamie attends his first school dance, and Lucas and Peyton take a road trip.

The families of Tree Hill draw closer as Lucas bonds with Jamie while working on Peyton's car, Sam develops a connection with Victoria, and Brooke and Haley throw Peyton a baby shower. Meanwhile, Nathan's ambitions seem closer than ever when he learns that an NBA scout will be watching his next game.

Lucas and Peyton's wedding day finally arrives, bringing some surprise guests along with it. Haley finds herself playing an unexpected role in the ceremony, as Skills and Brooke try to control Jamie and Nick. Meanwhile, Nathan continues to hope to be drafted into the NBA.

Tree Hill bids goodbye to the past while anticipating the future: Lucas and Peyton prepare for the birth of their child with the help of a surprise visitor, Dan nears his end, and Brooke works with Victoria to relaunch Clothes Over Bro's. Meanwhile, Nathan returns to Tree Hill to face Haley and Jamie after being released from the Chiefs.