Middle-aged Xu Men Gan thought she had everything under control, but her life suddenly went out of control. The company laid off a large number of employees, promotion was blocked, her husband Li Lin lost his job, her daughter was suspected of premature love, and she unexpectedly had a second child. All these problems came at once, leaving her exhausted. How to find the motivation to start again under the pressure of reality and strive to balance between self-growth and family responsibilities are the problems she needs to solve urgently.

On the other hand, her best friend, Chen Wan Zhen, was ignored by her husband, Yu Hai, in her life as a full-time housewife. She was so distressed that she decided to return to the workplace. Xu Men Gan's sister, Xu Meng Xin ​, suffered from hormone imbalance during pregnancy. In the struggle and pain, they overcame the difficulties with softness and finally opened up a new situation in life and achieved a second growth.

人到中年、以為一切盡在掌握中的許夢安（秦海璐飾）生活驟然失控，公司大面積裁員、職場晉陞受阻、老公李臨（保劍鋒飾）失業、女兒疑似早戀、不期而至的二胎等問題一股腦兒湧來，讓她心力交瘁。 如何在現實壓力中找到再出發的動力，在自我成長和家庭責任間努力平衡，是她亟待解決的問題。 另一邊閨蜜陳婉真（左小青 飾）在全職太太生活中，被老公於海（田雨 飾）漠視，備受煎熬的她決定重返職場。 許夢安的妹妹許夢心（潘之琳飾）則飽受孕期激素失調的折磨。 她們在掙扎和痛苦中，以柔克剛，最終打開人生新局面，獲得第二次成長。

人到中年、以为一切尽在掌握中的许梦安（秦海璐饰）生活骤然失控，公司大面积裁员、职场晋升受阻、老公李临（保剑锋饰）失业、女儿疑似早恋、不期而至的二胎等问题一股脑儿涌来，让她心力交瘁。如何在现实压力中找到再出发的动力，在自我成长和家庭责任间努力平衡，是她亟待解决的问题。另一边闺蜜陈婉真（左小青 饰）在全职太太生活中，被老公于海（田雨 饰）漠视，备受煎熬的她决定重返职场。许梦安的妹妹许梦心（潘之琳饰）则饱受孕期激素失调的折磨。她们在挣扎和痛苦中，以柔克刚，最终打开人生新局面，获得第二次成长。