When an innocent couple is murdered execution-style in the Arizona desert, it marks the beginning of a 50-year search for the truth. After decades of investigation, the controversial case remains shrouded in mystery including a claim that an innocent man was framed by his ex-wife for both murders.

Young mother Rhonda Boggs is stabbed to death in her kitchen and the only witness is her 2-year-old daughter. What the child witnessed aids the cops to catch the killer's trail.

17-year-old Joanna Rogers disappeared from her home in the middle of the night in Lubbock, TX, and her body is later found dumped in a landfill. The investigation is aided by evidence from another brutal murder case. Police painstakingly track leads, including of all things, a barcode tag on luggage found in a landfill.

Police are called to the scene of a tragic car wreck in the Blue Ridge Mountains. But as investigators examine the crash site they realize Wendy Kratzert's death was no accident. As they follow a startling trail of betrayal back to their prime suspect, they uncover another mysterious disappearance.

Hillsborough County in Florida is in the midst of a horrifying crime spree with young women turning up dead every week. Teenager Lisa McVey's bravery helps to bring an end to a vicious killer's reign of terror.

When 17-year-old high school student Stacy Fairchild disappears from a mall parking lot in Lancaster, OH, on her way home from work, the police suspect kidnapping or murder and zero in on her suspicious soldier boyfriend, but they may be pursuing the wrong man. Later, another young woman escaped an attack inside a tanning salon and helped police link DNA from her attacker to the Fairchild mystery.

A beloved father of two is killed execution-style after a friendly game of poker turns deadly. It's up to the police to find out the real truth behind the the crime.

A couple is gunned down in a savage attack while in Washington, D.C., and the killer leaves almost no clues. When another similar murder is discovered, the mystery starts to unravel and police are led to an evil beyond imagination.

An innocent mother of two is mysteriously gunned down on her way to work in downtown Philadelphia. Despite the fact that surveillance cameras recorded every detail, including the killer's getaway, but the footage does not reveal his identity.

A 20-year-old woman goes missing after a night out with friends, and police are baffled. The disappearance remains unsolved for a decade, until a cold case investigator and an undercover sting operation uncovers dark secrets that blow the case wide open.

In the span of 8 months, 3 young girls are kidnapped from their homes in Virginia and murdered. As police hunt for the killer, he strikes again, and a young girl's heroic actions crack the case.