The team finds three young women, all of whom appear to have been brutalized in the same way. The only witness they have is the surviving young woman, who can communicate only through blinking. Photographs found at one of the crime scenes lead the team to a couple that had sponsored one of the victims, and the boyfriend who claims he hasn't spoken to her in weeks.

Junkie Jordy Thompkins was shot dead in an alleyway, but the bullet that killed him is missing. Taylor and Hawkes soon realise that a rat may have eaten the bullet, and finding the rat leads them to a robbery that occurred earlier that day. After Robin Prescott is found raped and beaten in Central Park with only a peony leaf on her clothing, Stella and Flack have the daunting task of trying to find the man who raped her, but Prescott has no memory of the crime.

After a skeleton is found on a tour bus and turns out to be over a decade old, Mac and the team use the backpack they have found to track the belongings to a young man named Aaron Moreland, only to learn that the body they have cannot possibly belong to him. By tracing the victim's shirt, detectives are led to a youth center worker who claims not to remember the boy, but is hiding an old secret of his own.

On the very night that he wins a D.J. competition, DJ Banner is found dead in an alleyway outside the club where the contest is being run, prompting Mac and Flack to investigate not only the club but also Banner's primary competition, who was jealous that his girlfriend's voice was part of Banner's act. Stella and Danny investigate the death of fashion designer Deborah Gayle, found face-down in the pool at her apartment by her assistant, who isn't concerned by her boss's demise. An autopsy reveals that the cause of death was poisoning by tetrodotoxin, a poison found in blowfish, which leads Stella and Danny to Fuqua Sushi.

Stella and Aiden investigate after finding the body of a teenage girl in a creek. They soon realize that she was a middle-class girl attending a fancy school who was trying to make it seem like her family had more money than they did, and trace her movements to a nightclub. Mac and Danny investigate when a body is found in the tunnels without any protective gear on, and end up running into a brick wall when the Sandhogs union blocks many of their attempts to get information about the victim.

Two cases. One involves multiple homicides at a restaurant and the other starts with an amputated leg found in a dumpster.

When the charred bodies of two men who had been robbing a Chinatown bank are found, the entire team investigates the crime, which leads them to Doris, the missing infant of the bank's manager. The team realises that Joanna Cho assisted with the robbery out of fear for her daughter's life. Mac and Stella finally manage to track down the third robber, only to find him lying in a pool of blood, with a trail of bloody baby handprints leading away from the body.

Danny and Mac investigate after a briefcase belonging to Luke Sutton is found left in the NYMEX with a bloody note inside. Their investigation into Sutton's activities lead them to Nick Lawson, whom Sutton had been investigating for illegal trades, but who swears he had nothing to do with his disappearance. Stella and Flack investigate the death of Trina Rolston, a young pregnant women who fell to her death from the roof of a church. With Hawkes help, Stella realises that the body was thrown off the roof to mask the true cause of death. The detectives soon realise that their two cases are connected.

After mounted officer Valasquez is shot down in the park, Mac goes looking for the bullet that killed the officer only to learn that it is lodged in the horse's spine and cannot be removed without being fatal to the horse. The investigation leads them to a local street vendor, but stalls when the D.A. asks Mac not to do anything to risk the horse until after the woman who donated it has a chance to say goodbye. Aiden investigates the body of a young man, Lenny Starks, who was found face-down, dead in the street. Aiden traces the young man to a local pizza parlor where she faces intimidation from the bookies who use it as a gambling front.

Mac and Stella investigate the murder of a woman who was stabbed in the heart with a wooden stake. The police arrest a woman who was kneeling over the body with blood on her, but Mac isn't convinced that she committed the crime.

A young John Doe, nicknamed 'Slick', is found lying across the rails of an underground subway. At first, he appears to have died from third-rail electrocution, but an autopsy suggests that he may have met his end by other means of electrocution. Meanwhile, Leo Whitefield is found shot dead at close range in a gallery he owns, with no sign of break in or theft, and a construction worker turns up with a fatal injury to the head.

Mac, Aiden and Flack investigate when Elaine Curtis is found dead at a dog competition, a knitting needle sticking out of her chest, and no shortage of suspects ranging from judges to trainers to contestants. Stella and Danny investigate the death of bicycle messenger Michael Starling, but the crime scene may have been anywhere along his route.

The detectives investigate a murder at a grocery store that is also connected to the death of a young man with the tattoo "Tanglewood" on his back. A third case involves a woman who was killed in a hit-and-run auto accident.

The body of a young contortionist is found folded into a box on Coney Island, leading Mac and Stella to the circus where they find themselves embroiled in a real-life Romeo and Juliet story between the dead contortionist, Lukas, and a trapeze artist, Anasuya. Danny and Flack find a woman's body in a laundry chute and learn that she was actually the former sorority sister of the woman who lived in that building, and turn their suspicion to the abusive husband the woman was hiding from.

The team's investigation into the death of Hannah Bloom, who died at her own wedding, is put on hold when her father refuses to allow them to perform an autopsy until after his daughter's body is blessed by a rabbi. Danny and Mac turn their attention to the woman who trained the doves who were supposed to be released, but cannot tie her directly to Bloom, who died from formaldehyde poisoning. Stella, Flack and Aiden investigate when a hand is found deep underground, and soon realise that the dead man, Rick Amadori, chewed off his own hand. It seems like a slam dunk when the son of a man Amadori killed three years earlier confesses to the crime, but things aren't as easy as they seem.

A woman's death leads our detectives to a school for sexual fetishes such as bondage and spanking.

When young gang members murder the owner of an upscale Bronx wine store, the CSI’s must work to find evidence that ultimately ties someone to the crime. Tempers flare when the murder investigation reunites Detective Flack with his long-time mentor and friend Sergeant Gavin Moran, who was the first to arrive at the crime scene. Meanwhile, Danny and Aiden investigate the death of an influential movie producer found dead on the canopy of his Chelsea apartment building.

When the chief investigator of a controversial report documenting corruption within the NYPD is gunned down the day before his findings are published, Mac and Stella must find the killer, launching a massive search that makes every officer listed in the report a suspect. Meanwhile, Danny and Aiden investigate the murder of a gypsy cab driver.

When the body of a young woman is discovered at a laundry facility, the bed sheets she is wrapped in lead Mac and Stella back to an upscale New York hotel that houses diplomats from around the world when the United Nations is in special session. Meanwhile, Danny and Aiden investigate the death of a homeless man found dressed as a human statue. By all accounts, the prank is deemed a misdemeanor, but Danny decides to delve further and his refusal to stop the investigation puts him at odds with Mac.

When a college student is beaten, shot to death and his apartment ransacked in what appears to be a drug-related hit, the team must track down his killers. After examining the evidence in the murdered student's apartment, the team finds traces of pure, unprocessed heroin and discovers that the victim had a female roomate who is now missing. Meanwhile, Stella's aggressive interrogation tactics with a witness threaten her police badge.

A nanny is found dead near a park while Messer is in trouble when he may have shot another police officer.

The team examines the murder of an avid Boston Red Sox fan found dead with a ruptured spleen following a tough loss against New York. Danny must put his baseball skills to the test to piece together the evidence as the CSIs try to find out how and why he was murdered. Meanwhile, after testifying in a murder trial, Mac is confronted by the defendant, Quinn Sullivan, who questions the validity of the evidence. Mac is torn between trusting science or his desire to help a man facing jail time who swears he's innocent. Also, when a truck kills a barely clad woman early one morning, the team investigates why she was running through the streets and from whom.

While Mac dines at his local breakfast spot, a gunman opens fire, leaving a waitress critically injured and a man dead, and Mac having to choose whether to chase after the suspect or save the life of the young woman. Meanwhile, before the chaos, Mac was approached by a shy patron who awkwardly engaged him in conversation. After feeling that he saved her life during the shoot out, she asks him to join her for a drink and Mac must decide if he is ready to start dating after his wife's tragic death.

Stella and Danny investigate when a jewellery designer is found dead, wearing the eight million dollar bra he created, and investigate the model he had shot and her bodyguard. Aiden begins to take the rape case she has been working on a little too personally, and is determined to stop the man before he can rape again. Hawkes gets to go into the field for the first time as he assists Mac in investigating the death of a man who liked to climb skyscrapers.

Stella and Danny are heading into the world of cuddle parties: non-sexual events were adults learn to touch and hug each other. Meanwhile, Mac, Hawkes, and Flack investigate the death of a hated plastic surgeon found covered with lye with thousands of eyewitnesses during rush hour at Grand Central Station. While Mac and Stella assist Aiden in a rape case, after she breaks an evidence seal, Mac must come to terms with Aiden's action and work up the nerve to fire her.

Mac and Danny look into the mysterious death of a man torn apart by tigers at the Bronx Zoo, which leads them to both the dead man's meat packing plant as well as his mafia relatives. Hawkes and Stella are left with the case of a beautiful young debutante found dead on the carousel only hours before her coming out.

Three cases. A murder during the Feast of San Gennaro with ties to a financial services company. A body sitting upright on a Central Park bench. An apartment fire where a 10-year-old boy died of smoke inhalation.

Mac, Stella and Flack investigate the death of a young dancer who recently won the lottery, and it isn't long before they realise that her death is connected to Lindsay's investigation concerning the death of a tram driver. Danny and Hawkes look into the murder of a local fish merchant, and soon find their way to a jealous friend who was angry that their child didn't get into a prestigious school.

When a man is found murdered in an elevator, Mac, Flack, Danny and Lindsay investigate a world where very young girls enjoy sexual encounters with much older men. They're left trying to determine whether their best lead is a suspect, a witness ... or the intended victim. Stella and Hawkes investigate the death of a young man found in Central Park who died from an extreme allergic reaction and learn that he had been pretending to be someone that he wasn't.

(Crossover episode with CSI: Miami, Season 4 Episode 7.)

Horatio Caine follows Henry Darius to New York so that he can keep his promise to a young boy in Miami, but by the time he and Mac are able to locate Darius he has disappeared again, leaving behind six more bodies. A link to the younger sister of one of the victims who was also Darius' hostage turns out to be a dead end, but Mac and Horatio soon find the connection between Darius and his hostage, leading them to a psychiatrist who had treated both.

Mac and Stella investigate a murder of a host of a high stakes poker game after a player was caught cheating and kicked out of the game. While Danny and Hawkes follow the clues that'll lead them to solve the death of a weather girl.

Mac, Danny and Lindsay investigate the death of owner of a doll hospital. Stella and Hawkes look into the death of a woman with terminal cancer.

Mac and Stella work on the case of a female roller derby player. Danny and Hawkes look into the murder of one of New York's upcoming crop of writers.

Danny and Stella find innovative ways to process a crime scene while Danny is trapped in a panic room with the victim, who was the only person with the security code. As a locksmith works to cut through the titanium doors, the CSIs rush to process the evidence before the victim decays further and Danny's oxygen runs out. Meanwhile, Mac, Dr. Hawkes and Lindsay investigate the murder of an exotic dancer found dead on a klieg light

Mac, Danny, and Dr. Hawkes investigate the death of a runway model who collapsed during a fashion show. Meanwhile, Stella, Detective Flack, and Lindsay investigate a teriminally ill patient's confession to the murder of his doctor.

Danny is on his way home after a long shift and finds Randy Williams subway surfing. Mac and Lindsay arrive on the scene and begin to wonder if Randy Williams died from riding on top of the subway. His death is even more suspicious after they examine the body more closely.

Stella is invited to an art gallery where she sees several paintings done by an artist named James Golden. Stella thought she was going to Frankie's place and not to an art gallery. Outside the exhibit two people are kissing and one of them is shot in the back with an arrow.

Lindsay, Stella, and Mac are on the case of a dead ADA, who they discover, is involved in a "kill war" with water guns. Meanwhile, Danny and Hawkes investigate the murder of a young lady who had a penchant for suing restaurants and taking them for all they are worth.

After the body of a dead woman is found in a water tower the team suddenly realizes that the building may hold a bigger mystery than they expected.

A young boy witnesses the death of a museum curator but doesn't want to tell anyone about it. Danny investigates the death of an urban golfer found dead on a construction site.

The life of a transplant patient hangs in the balance as the team tries to find the hijacked plane carrying the liver.

A man dressed in a superhero costume is found dead in an alley, after saving a man being mugged. Mac, Stella, and Dr. Hawkes find his clothes in a nearby phone booth. Danny and Lindsay investigate the murder of an NFL first-round draft pick, known as "Superman."

Mac receives a phone call confessing to an old murder before the caller commits suicide. The call leads the team to a football stadium to uncover a body and they learn the suicide victim belongs to the Tanglewood gang. They also find a cigarette that puts Danny's job on the line after his DNA is found on it.

Stella and Danny investigate the death of a businessman who used the services of an expensive call girl service.

Mac and Lindsay question Kid Rock because he was the last person to see his limo driver alive when the driver is found dead in the alley just before Kid Rock’s encore performance concert.

Two women both claim to be the wife of a murder victim surprise Mac and Stella at the circumstances of their relationships. Both women have been in a trinogamous marriage with the victim. Meanwhile, Danny and Lindsay investigate the murder of a young woman who is found off a dock tangled up in kelp while she is dressed as a mermaid.

Mack and Danny investigate a Marine found dead in Central Park during Fleet Week. The evidence doesn't add up and who is Ellie? Stella, Lindsay, and Hawkes investigate a dead body found in a burnt out car. The results of their investigation leads to a devastating loss for the whole team.

After a routine call leads two of the team into finding a bomb, they evacuate but a few are still in the building along with Mac and Flack when the bomb detonates. After the explosion the CSI's face a race against time to find the bomber and the possibility of losing one of their own. Mac must come to grips with having let a Marine die in Beirut in 1983.