When Kim's parents chaperone a school ski trip, she is greatly humiliated. Meanwhile, a mad geneticist threatens the trip.

When Ron is volunteering to help the elderly by doing tasks for them, Ron is assigned to the house of Timothy North, an elderly man who has sent all volunteers away. However, Ron stumbles across the fact that Timothy North is really The Fearless Ferret, an old superhero who Ron adores; in which Ron is selected to become the new Fearless Ferret but he must keep his identity a secret, even from Kim. Though when The White Stripe comes to fight the new Fearless Ferret, Ron discovers it’s more difficult than he expected; while Kim is busy trying to figure out why Ron is behaving strangely.

When Dr. Drakken is ordered by his mother to look after his cousin which turns out to be Motor Ed, Drakken and Motor Ed work together to complete a “Doomvee”, which is a Humvee that is full of superior weaponry. Meanwhile, Kim is feeling alone because Ron is spending the weekend with Felix instead of her, which causes her to become desperate because she needs some social interaction. Kim attempts to hang out with Ron and Felix despite the fact that she hates doing whatever they do, but when Dr. Drakken and Motor Ed steal Felix’s wheelchair, they work together to see if they can retrieve his wheelchair back and put an end to their evil plan.

While trying to stop Dr. Drakken, Kim gets into a fight with Shego in which they accidentally get a microchip attached to each of them that can control their emotions. However, when Ron accidentally picks up the control device instead of Kim’s communicator, he thinks it’s a game and he inadvertently controls Kim and Shego’s moods, in which he puts on romance mode before he and Kim go to school. Ron must now deal with Kim’s sudden advances towards him while trying to determine what he should do about the situation, all the while Drakken is dealing with a suddenly love-stricken Shego.

Ron steals Kim's supersuit to use in the upcoming football game. Meanwhile, Professor Dementor becomes jealous of the suit and devises a system to control it.

Jim and Tim decide to take on the duties of the Middleton Mascot and Ron takes it upon himself to train them. Meanwhile, Drakken is broken out of prison by an alien named Warmonga.

After discovering Hana walking on the ceiling, Kim and Ron try to get to the bottom of Hana's secrets. Meanwhile, Monkey Fist finds an ally in Yono the Destroyer as he continues his search for the "secret weapon".

High school graduation nears for the senior class, but Warmonga's return jeopardizes everything as Team Possible goes through their toughest odds yet to save the planet.

After both Kim and Drakken have been taken captive, Ron and Shego must race to rescue them from the clutches of Warmonga, Warhok, and the other invaders. All of the main characters must now band together to save the planet that they call home.