Drakken kidnaps Ron when he believes he is a super genius because Ron’s schoolwork has recently been completed by a brain ray-enhanced Rufus; while Dr. Drakken attempts to figure out the source of Ron’s knowledge, it’s up to Kim and Rufus to help rescue him and foil Drakken’s scheme.

Ron goes to ridiculous lengths to grab the attention of a pretty girl at the theater. Meanwhile Kim uncovers a conspiracy at the Space Center involving top secret technology, battle robots, and a disgruntled former employee. In the process of solving the mystery, she is suspicious of the idea of a seemingly innocent being the culprit responsible.

When Señor Senior Sr. becomes disappointed in the way his son’s villainy is handled, he decides to hire a tutor to ensure his son’s success; which turns out to be Shego. Meanwhile, a hopeless Kim is stuck on Home Economics with Ron but when Ron becomes an expert chef while Kim can’t cook a single thing, Ron is chosen to help Kim out. Can Kim overcome her predicament or is this one sitch that she cannot escape from?

When Dr. Director at Global Justice decides that it's the "Ron-ness" that's Kim's secret to success, Ron goes under the microscope. Unfortunately, this means being stolen by the lackey-intolerant Gemini, Dr. Director's older twin. Global Justice, Kim, and Rufus take on Gemini's fist of fury (and Pepe the neurotic Chihuahua) to recover the Ron Factor.

Kim and Ron are taking Drivers Ed, which most of the students are nervous but Kim remains confident that she’ll do a good job. However, when she chokes up and fails the initial test, she soon learns that the pressure of the test is far greater than any foe she has fought. Meanwhile, Dr. Drakken has kidnapped a scientist who specializes in artificial intelligence, Kim gets a visit from an unexpected guest that may be able to help her out.

When a diamond is stolen, all the signs indicate that a Lithuanian Wolfhound breeder named Falsetto Jones is the thief. Kim and Ron enter Rufus into a dog show as a Peruvian Hairless in hopes of confronting Falsetto and getting the diamond back, though will Rufus actually be able to play the part?

Kim's canon of villainous foes go hunting for Naked Mole Rat when Rufus becomes the carrier of a much-coveted micro-decoder … all while Kim is pet-sitting for Ron.

It’s career day and Kim expects to be paired up with her mother. However, when Bonnie gets teamed up with her instead, Kim gets stuck with a janitor who seems too dedicated to his job. Meanwhile, Ron gets paired with a secret agent and gets a plethora of unique gadgets to try out. However, with Dr. Drakken stealing a weather machine so he can flood Canada, Kim may just realize that her mentor may be more useful than she first thought.

Kim, Ron and the Possible family head to Florida to help Kim's grandmother unpack at her new home. Can Kim fight against her grandmother's over-protectiveness? Meanwhile, Drakken and Shego accidentally create an army of old people instead of teens, and Kim's Nana is one of them. Can Kim fight her own Nana?

Ron is sucked into the cyber game world of Everlot as he attempts to impress Zita. The whole gang duels Malcolm the Wraithmaster LotR-style, with a little help from a not-so-naked Tunnel Lord.

When Middleton High School participates in a student exchange program, Ron is selected to go to a school in Japan while a student named Hirotaka is chosen to come to Middleton. Ron finds out that the school he was assigned to visit is a secret ninja school while Kim and Monique eventually start crushing on Hirotaka. However, when Lord Monkey Fist steals the Lotus Blade from Ron’s sensei, it’s up to Ron to save the day; though without Kim’s help.

Drakken and Shego attempt to breach Area 51 with a gigantic poodle while Ron uses the attack to shoot his monster movie.

The weather outside is frightful when evil, toxically-mutated snowmen terrorize Middleton.

In the spirit of the season, Drakken, Shego, Ron, and the Possible family put their differences behind them to share Christmas in the Arctic ... of course, only after several action-packed battles and confrontations.

When a recent string of thefts cause a global shortage on a certain type of doll, Kim decides to investigate, despite the fact that she already has a lot of extra-curricular duties to perform. When she finds out that the Bebe-bots are back and bent on creating an army of their speedy species, with Bonnie as their queen, Kim must rely on some recently acquired experimental shoes in order to save the world; though that isn’t going to stop her from doing a few of her extra-curricular tasks along the way.

Ron signs an unwilling Kim up for the school talent show after Bonnie announces her intent to crush any competition. Her plans to sing are interrupted when Wade begins acting erratically and orders Kim and Ron to recover teleportation technology from Professor Dementor. Technology, she suspects, that may have not been stolen after all.

On their way to cheer camp, the squad again finds itself at Camp Wannaweep for the Spirit Stick Competition. Kim deals with having an obnoxious Bonnie.

On their trip to Go City, Ron and Kim come across a villain named Aviarius who is seeking the power of another hero. However, when Kim inadvertently winds up with the a hero named Hego’s powers, she soon learns that the only way to restore what isn’t hers and to help stop a mad man may be to team up with her deadliest foe; Shego.

When Kim catches a cold from her brothers before a mission, she soon discovers that it’s hard to save the world when you’re not feeling well. Dr. Drakken and Shego exploit the moment to steal a laser from the research lab Kim is guarding. However, when Kim’s sickness begins to spread, a series of events occurred that not even she could expect.

When Kim is sprayed with some pollen that causes her to vanish more and more each time she blushes, she must stay at home while Ron and Wade work together to find the cure. However, when Josh Mankey asks Kim on a date, she risks her life to go out with him; though Drakken and Shego take notice of her foolishness and exploit the opportunity to make it one of the most embarrassing nights of her life.

Kim, hoping not to be landed with Ron as her science project partner, instead gets a brainiac who won’t let her do anything at all. Monique gets Ron and quickly becomes exasperated by his trademark laziness. Meanwhile Drakken charms DNAmy into creating a vicious Komodo dragon.

To help his son's ongoing quest to become a pop sensation, Senor Senior, Senior kidnaps the Oh Boyz band to blackmail the record company. The plan backfires when Ron winds up captured along with the group. The record executive, finding the Oh Boyz' disappearance to be a profit windfall, is in no hurry to help so Kim must find Ron and the others on her own.

Kim catches a nasty cold from the Tweebs, but still accepts a mission to guard a mysterious machine. After Drakken and Shego steal the device, her mother insists that she stay in bed to rest while Ron and then the Tweebs take up her duties. By the time matters are resolved, everybody on both sides of the conflict has caught the cold.

When trying to save a scientist from Dr. Drakken’s secret arctic base, Kim and Ron are hit with a truth ray which forces them to speak the absolute truth about every issue. Kim soon discovers that this is a huge embarrassment while Ron is enjoying his newfound truth potential, but can they get through the day without causing themselves huge problems?

As a part of Mother's Day mother-daughter bonding, Kim and her mother Dr. Possible decide to foil Drakken's latest scheme together. Drakken, on his part, is forced to deal with the presence of his mother while he attempts to steal a batch of Syntho-Plasma.

After a series of high tech robberies, Kim tries to stop the plot of a rogue scientist turned rocking trucker, with a little help from a new friend, Felix.

Naco royalties make Ron a tremendously rich and wealthy multimillionaire with ninety-nine million dollars, which he then proceeds to squander on a posse of fake friends and spending binges. Out of greed, Dr. Drakken attempts to steal Ron's newly acquired fortune and wealth to complete his latest doomsday scheme.

After a long list of attempts to turn himself into a jock go sour, Ron gets a new chance to compete in the X games when he and Kim are sent to investigate a series of robberies.

While Kim and Ron are at the Museum, she discovers that one of her ancestors was a thief and she decides to figure out what really happened in order to clear her family’s name. However, after a bunch of bizarre coincidences connects the events on that day with that of Wade and Dr. Drakken’s ancestors as well, she soon believes she may be close to figuring out what exactly happened to cause her ancestor to get framed, though Ron keeps feeling that something about their predicament just doesn’t feel right.