Ray and Slimer have been in a joking mood lately, but things are about to get worse when a magical box is opened and releases two imps that like to play deadly practical jokes.

Investigating a bizarre tornado in Central Park, the Ghostbusters are tossed into another dimension, a strange place that is exactly the opposite of New York City. In a world populated by ghosts, the heroes must evade capture by their own ghostly counterparts, the human-hunting Peoplebusters!

A Werechicken strikes an unsuspecting farmhouse, leaving a trail of mayhem and one very large egg. After a hungry Slimer tries to cook the egg and unintentionally hatches it, the newborn Werechicken bites Egon, turning him into a half-man, half-chicken creature!

Janine falls head-over-heels for a wealthy industrialist who uses her friendship to gain acess to the Ghostbusters' files, from which he creates the Robo-Buster X-1! Now, the manufacturer claims the Robo-Buster doesn't merely contain spirits.. It actually destroys them!

The Ghostmaster general, tired of the Ghostbusters' constant interference, sends three ghostly bounty hunters to eliminate the heroes at the firehouse. In the ensuing battle the Ghostbustesr are reduced to six inches in height!

At an Eastside wrecking yard, a pit of toxic liquid waste has an evil effect on a long dormant Indian earth spirit. When polluted, the once benign spirit rises from it's sacred resting grounds and takes possession of the Ecto-1, causing the hearse to come alive!

At an excavation site in Brooklyn, workers accidentally uncover a dimensional gateway to the world where all lost objects go. The Ghostbusters are called in to help plug the ever-widening chasm and discover that the company is run by someone very close to Winston.