When a young girl is killed in a drive by shooting a young 14 year-old boy is quickly arrested. The boy, Ethan, was part of a special program trying to get kids out of gangs and trouble. Ethan denies having had anything to do with the shooting, but if he doesn't tell who did do it or if Quincy and the probation people cannot find them then not only will he end up in prison but the special program will be closed down.

When a young mother suffers from a nerve disease, Quincy fights the drug companies and the government to get her the medication she needs.

A medical examiner starts making basic mistakes, mistakes that are putting her job on the line and are caused by her alcohol binges. She is heading deeper and deeper into alcoholism and it may be that only Quincy can help her before she falls too far.

A new pathologist (Walter Ross) is working in the lab who is disabled. When he looks into a case of electrocution of a handicapped baby (Sturge – weber disease) he is convinced that the baby was murdered by its father, Quincy's friend, Gerald Preston.

Quincy is alarmed at Walter's blinkered view and decides to investigate Walters findings for himself.

Gerichtsmediziner Quincy soll in der Kleinstadt Mill Falls einen Mord aufklären. Henry Moeller, der seine Mitmenschen regelrecht schikaniert hat, wurde ermordet. Für Quincy ist der Fall ein Rätsel, da auf einmal sechs Männer behaupten, den unbeliebten Moeller ermordet zu haben. Was steckt hinter dieser Verschwörung?

A sick woman with cancer leaves the hospital and dies. Those that have had physical contact with her die. Quincy soon discovers a new virus is the culprit of the deaths and hurries to find the cause.

Emily comes to see Quincy about a young 18 year-old boy he has just completed an autopsy on. He died while slamdancing at a punk rock club, killed while dancing to lyrics about death, lack of hope and violence. She had been counseling his girlfriend Abby and is worried about her. Quincy's report declares that the punk music Zack listened to was a part of the cause of his death but the main reason was an ice pick in his back. Punk music and its lyrics come under the spotlight as Quincy tries to find evidence to prove who killed Zack.

During an attempted armed robbery a hostage is shot by a police officer by accident. The police immediately suspend him and threaten to kick him off the force. He wants Quincy to use his forensic skills to defend him and prove that the shooting was righteous.

Michael Moroshima, a cop working undercover with the Asian task force and Sam's best friend, is killed while listening in on a deal between the Yakuza and the Mafia. Sam explains to Quincy all about the Yakuza and the Japanese code of honor that means his friend's father will try to find his son's killer and exact revenge. Sam tries to prevent this from happening but finds himself getting into deeper trouble himself.

At the end of a school day a young girl gets into a cab for her daily ride home. She doesn't arrive there and a search is soon started. The real cab driver is soon found and he gives a description of the man who attacked him and the cab is soon found abandoned and examined for forensic evidence.

Then all of a sudden a man who fits the description walks into a police station. He is alone and refuses to confirm or deny anything. All he will let the authorities know is that Quincy and Professor Hillman (the kidnapped girl's grandfather) are covering up a murder.

After his furniture warehouse is burnt down Ted Locke, a friend of Quincy's finds he is suspected of arson and murder. A lack of evidence makes the DA reluctant to press charges though. Enter Federal Prosecutor Philip St.John, he suggests avoiding a normal court trial and charges Locke with mail fraud, based on his claims for payment from his insurance company, which allows him to bring him before a Federal Grand Jury. When the ‘trial' starts Quincy discovers that there a literally no rules in a grand jury and the defendant can have no representation to help in defending himself. Quincy decides that he is not going to stand for this and tries to help his friend out.

The body of a young girl is found at the side of a highway. Quincy determines that the body was moved after she died. Monahan thinks that her boyfriend, Toby Kenyon, killed her but he tells the police that she killed herself. Quincy believes the boy and asks Emily to do a psychological autopsy on the dead girl. This involves talking to her friends, family and teachers about she acted and talked over the last few weeks of her life.

Bei der Explosion in einer Flugzeugfahrwerkfabrik wurde der Arbeiter Timothy Hurley tödlich verletzt. Der Untersuchungsbeamte Arnold Chatham wurde von der Staatsanwaltschaft beauftragt, den Fall zu untersuchen. Chatham deckt mithilfe von Quincy einen Versicherungsbetrug auf.

Bei den Ermittlungen gegen einen mehrfachen Sexualmörder bittet Lieutenant Monahan die Hellseherin Edith Jordan um Hilfe. Sie kann tatsächlich einen weiteren Mord verhindern. Als aber der Mörder Ediths Tochter bedroht, interpretiert diese aus Angst die Situation falsch. Zum Glück hat Quincy einen rettenden Geistesblitz.

An accident at a club leaves JJ Chandler, a top country singer, badly burned and in intensive care. Sgt, Wendell, a narcotics cop, believes Chandler freebasing cocaine caused the accident; the only problem is getting any proof, or a witness. While Wendell is trying to find someone who will testify Quincy begins to realize how many drug overdose victims he has dealt with during his time with the coroners office. He decides that there must be something he can do about it and means to do everything he can to stop the proliferation of drugs in Los Angeles.

Quincy and Emily's wedding is fast approaching and there are many things that still need arranging. Emily has brought in Winslow, a wedding arranger to help. While the wedding arrangements are proceeding a body comes into the coroner's office, an old man who died of natural causes in a rest home, just after his 65th wedding anniversary. After the autopsy the wife of the deceased man, Edna, comes in to see Quincy and tells him that she killed her husband.

Emily calls off the wedding when Quincy fails to make it to the rehearsal, the last straw as far as she is concerned. Quincy seems to be more interested in the tales Edna has to tell about her husbands' death. Was it murder as she claims or are her statements just the ravings of a mad woman?

Quincy and Emily receive the use of a Judge friends' mountain cabin for their honeymoon. They picture a long romantic week alone, skiing and sitting in front of an open log fire. When they arrive they are disappointed to find that there are other guests as well. All the guests are involved in law enforcement of some form or other and all know each other. They soon realize that the last time they saw each other al together was on when they all worked on the same case, a year ago. The man they all helped convict escaped jail and has never been heard of or seen since. When the judge doesn't arrive they all decide to go out looking for him in case there has been an accident. When they find his car, caught up in a snowdrift blocking the only way down the mountain, and his body inside it they all begin to worry whether the missing criminal is planning his revenge.

A midwife, Olivia, is approached in the street and asked to help deliver a baby. She knows that she should not get involved but can see that the mother's friend is desperate for help. She goes to their aid but the baby dies in childbirth. The hospital they rushed the baby to when it became apparent that she couldn't help decides that her negligence caused the baby's death. The next thing Olivia knows she is being arrested for murder! Dr. Reed, a friend of Olivia's, visits Quincy and asks him to do his own autopsy on the baby. She hopes that he will find something that will help clear her friend.

Dr. Asten asks Quincy to stop of on his way to his fishing holiday to do an autopsy on a young boy. The coroner in the area wants back up evidence to help him close down the foster child home that was looking after the boy and other children. To help out one boy Emily and Quincy get the local authorities to try out a new scheme. The idea of this scheme is that a qualified therapist lives with the troubled family to try and stop any flashpoints from occurring, hoping that this will then enable the family to be able to live happily together.

An old lady is attacked and killed in her own apartment. Quincy is horrified that someone could so callously attack an old woman and is determined to find evidence that will convict the killer.

Later, after an evening visit to her apartment looking for more evidence Quincy himself is attacked and mugged, leaving him scared to go out in the dark and making him jump at every sound.

An old lady is shot and killed by a burglar in her own home. When he arrives Quincy recognizes her as being one half of a couple of entertainers he saw in his youth. He remembers reading about their brilliance and wonders what happened to her old partner, Morris Perlmutter. He tries to find as much evidence as he can and then decides that he is going to find Morris. Meanwhile Morris is trying to get his big break in TV with the part of an old man in a play that is going to be broadcast live.

Kenny Kelso, a young father, is seriously injured in a work accident and loses his arm. His arm is found and the paramedics take both him and his limb to a new place, Experiment Hope, where it may be possible to reattach them. The Doctor in charge, Gabriel McCracken, is the man behind the revolutionary new techniques and does everything he can to make sure that Kenny will be able to use his arm again.