An alleged accidental drowning at a Health Spa pits Quincy against a slick attorney hired to prevent adverse publicity from affecting profits.

When a kidnapper dies in a car crash after trying to pick up his ransom the only clue that will help the police find the missing boy is a half eaten apple. It is up to Quincy to use his medical expertise to uncover where the kidnapped boy has been hidden.

An autopsy on a college football star reveals a congenital brain disease, and Quincy urges the victim's younger brother to stay out of the next high school game. But the boy's father and the school are determined to win the championship at any cost.

A fire in a small motel room causes the death of the single woman occupying it. The evidence shows that the identity of the woman is Jessica Ross, the country's top newswoman. As Quincy begins a press conference confirming her death Jessica walks in through the door, declaring that the rumours of her death are unfounded. Quincy and Asten are shocked but soon Quincy doesn't believe that this woman is Ross, and that his original findings were correct. He thinks that the body was Jessica ross and this woman is an imposter.

Quincy is gravely wounded at the scene of a crime, so it is up to Sam, Asten and Lt. Monaghan to solve the case he was working on and catch the person who shot him.

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Quincy delves into the world of cosmetic surgery after he autopsies a woman who killed herself because she hated the scars a botched operation caused. He discovers that the plastic surgeon isn't in fact a qualified plastic surgeon, only a qualified MD. The law allows anyone who has qualified as a doctor to call himself any kind of specialist he likes.

Monaghan asks Quincy to push the autopsy of a young car thief to the top of his priority list. The boys' friend is claiming that a police officer chased him down and killed him after they were stopped in their stolen car. When the autopsy is completed it can only confirm that the boy, Billy Harris, died to a bone broken in his neck, and not how it could have occurred. This information is enough to get the press printing stories of police brutality and a Californians for Constitutional Rights lawyer rushing in to defend Billy's friend Steve.

Quincy investigates the death of a teenager who smoked marijuana treated with a chemical that stimulates plant growth.

Quincy and Danny go to the tack and, while there, see a horse go wild in the stables. The horse kills one of the jockeys but, after completing his autopsy, Quincy thinks that it wasn't an accident! That someone murdered the man and tried to make it look as if the horse killed him. The problem Quincy has though is to actually prove his theory, and not even the purchasing of some horse hooves and the unusual step of autopsying a horse can help him. Though Asten has fits about the cost of both these steps to find the truth!

After performing an autopsy on a young woman Quincy finds out about a man called' Uncle Harry'. He preys on young girls, runaways, who arrive in Los Angeles alone and scared. Quincy helps Carol Treager, who runs a home for runaways whose lease is about to run out, to not only track down a missing young girl who was seen in the company of ‘Uncle Harry' but to also try and get a new place for her and ‘her' kids.

Two customs officers want Quincy's help in catching arresting a diamond smuggling ring. A courier they were following was killed when a bus at the airport and, as Quincy is going to a Las Vegas to judge a Miss Coroner Contest; they want him to take the couriers place. He has to deliver the diamonds to a known mobster, something he really, really does not want to do!

After Quincy's traces an old man's death to his son's physical abuse he is faced with a similar case involving the exploitation of two elderly women by their unscrupulous nephew.

President Sarejo, the ruler of a small South American country, has come to America for some urgent hospital treatment. He brings with him most of his cabinet so that he can keep an eye on them while away. What with them and the large number of his countrymen protesting outside the hospital there are an awful lot of people who may want him dead.

It isn't him who dies though; first one of his cabinet and then another die of suspected heart attacks.

Dr. Asten's niece is involved in a car accident while drunk and it is up to Quincy to try and establish whether she was the driver of the car or whether it was her friend, who died in the crash, who was driving. Asten gets Quincy to swap jobs with him for a day so that he can find out how hard it is to run the place.

Quincy is hired as a technical director for a movie that is recreating a famous homicide case. Watching the murder scene being filmed convinces him that the real murderer is still loose and that the woman in jail for the crime was innocent. He sets out to find the truth but is hampered by the reluctance of the woman convicted to get involved. She only has a few months now until her parole hearing and if she is still trying to prove her innocence she has no chance of getting out if Quincy fails to find the real killer.

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A truck driver dies just days after being splashed by a caustic chemical he was illegally dumping. Quincy uncovers the cause of his death and investigates further, trying to find where the chemicals were dumped before it rains and a dangerous chemical cloud is created.

After a life saving heart bypass operation Ted Markham's brother dies from complications. He is incensed that his brother died from what should have been a simple operation. He wants, and pays for, an autopsy from the Coroner's office and Quincy is given the job.

When he has completed the autopsy Quincy believes that the eminent surgeon, Dr. Royce, who was supposed to have done the operation didn't really do it. He thinks that a practice known as ‘ghosting' took place and that a young resident did the operation in his place.

A sick woman with cancer leaves the hospital and dies. Those that have had physical contact with her die. Quincy soon discovers a new virus is the culprit of the deaths and hurries to find the cause.

Emily comes to see Quincy about a young 18 year-old boy he has just completed an autopsy on. He died while slamdancing at a punk rock club, killed while dancing to lyrics about death, lack of hope and violence. She had been counseling his girlfriend Abby and is worried about her. Quincy's report declares that the punk music Zack listened to was a part of the cause of his death but the main reason was an ice pick in his back. Punk music and its lyrics come under the spotlight as Quincy tries to find evidence to prove who killed Zack.

Michael Moroshima, a cop working undercover with the Asian task force and Sam's best friend, is killed while listening in on a deal between the Yakuza and the Mafia. Sam explains to Quincy all about the Yakuza and the Japanese code of honor that means his friend's father will try to find his son's killer and exact revenge. Sam tries to prevent this from happening but finds himself getting into deeper trouble himself.

After his furniture warehouse is burnt down Ted Locke, a friend of Quincy's finds he is suspected of arson and murder. A lack of evidence makes the DA reluctant to press charges though. Enter Federal Prosecutor Philip St.John, he suggests avoiding a normal court trial and charges Locke with mail fraud, based on his claims for payment from his insurance company, which allows him to bring him before a Federal Grand Jury. When the ‘trial' starts Quincy discovers that there a literally no rules in a grand jury and the defendant can have no representation to help in defending himself. Quincy decides that he is not going to stand for this and tries to help his friend out.

An accident at a club leaves JJ Chandler, a top country singer, badly burned and in intensive care. Sgt, Wendell, a narcotics cop, believes Chandler freebasing cocaine caused the accident; the only problem is getting any proof, or a witness. While Wendell is trying to find someone who will testify Quincy begins to realize how many drug overdose victims he has dealt with during his time with the coroners office. He decides that there must be something he can do about it and means to do everything he can to stop the proliferation of drugs in Los Angeles.